DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PGAP3 and Pgap3

DIOPT Version :9

Sequence 1:	NP_610223.1	Gene:	PGAP3 / 35570	FlyBaseID:	FBgn0033088	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	NP_001137367.1	Gene:	Pgap3 / 688174	RGDID:	1592386	Length:	320	Species:	Rattus norvegicus

Alignment Length:	321	Identity:	132/321 - (41%)
Similarity:	188/321 - (58%)	Gaps:	15/321 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 SAIVLLLGALVTACLASNGDRTQFFHNCRQNCERTNCSADGLEIQEQAVKFY--QQSVFDRLFQW 69
            :|.:|||...|....:|.|||...:.:|...||..|||.|       |:|.:  :|.::..|..|
  Rat     5 TAPLLLLTLAVGLAGSSQGDREPVYRDCVLRCEERNCSGD-------ALKHFRSRQPIYMSLAGW 62

  Fly    70 SCADECQYGCMWRTVFAFFERGWPIPQFYGKWPFLRLLGMQEPASVIFSCLNFVVHLRLLRKFRR 134
            :|.|:|:|.|||.||..:.:.|:.:|||:|||||.|.|.:|||||.:.|.||.:..|.:|.::|.
  Rat    63 TCRDDCKYECMWLTVGLYLQEGYRVPQFHGKWPFSRFLFIQEPASALASLLNGLASLVMLCRYRA 127

  Fly   135 EVRPDSPCYMLTHIFAVTSLNGWIWSAIFHTRDFPLTELLDYAFAYSIILCSLYVMVMR---MLH 196
            .|...||.|.....||..|||.|.||.:|||||..|||.:||..|.::||.|:|:..:|   :.|
  Rat   128 SVPASSPMYHTCMAFAWVSLNAWFWSTVFHTRDTDLTEKMDYFCASAVILHSVYLCCVRTVGLQH 192

  Fly   197 RYSLFLRGVITLAFLSYYINYFAYLSVGRFNYAFNMMVNVATGVIAAVGWFVWCHFVRTRRPYFR 261
            .......|.:.|..|:.:|   :|||:..|:|.:|||.|||.|::....|.|||.....|.|:.|
  Rat   193 PTVASAFGALLLLLLTGHI---SYLSLVHFDYGYNMMANVAIGLVNLAWWLVWCLRNHRRLPHTR 254

  Fly   262 RILRFYILMALAMSLELLDFPPILWILDAHALWHLATIPLASLYYDFMIEDCRTLRKEKAA 322
            |.:...:|:.....||||||||:.|:|||||:||::|||:.:|::.|:.:|...|.||..|
  Rat   255 RCMVVVVLLQGLSLLELLDFPPLFWVLDAHAIWHISTIPVHTLFFRFLEDDSLYLLKESEA 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PGAP3	NP_610223.1	Per1	65..313	CDD:282000	108/250 (43%)
Pgap3	NP_001137367.1	Per1	54..305	CDD:397963	108/253 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338215
Domainoid	1	1.000	220	1.000	Domainoid score	I2541
eggNOG	1	0.900	-	-		E1_COG5237
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5484
Inparanoid	1	1.050	246	1.000	Inparanoid score	I3193
OMA	1	1.010	-	-		QHG59972
OrthoDB	1	1.010	-	-		D523376at33208
OrthoFinder	1	1.000	-	-		FOG0004451
OrthoInspector	1	1.000	-	-		oto97188
orthoMCL	1	0.900	-	-		OOG6_104144
Panther	1	1.100	-	-	LDO	PTHR13148
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3155
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.810