DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PGAP3 and Pgap3

DIOPT Version :9

Sequence 1:	NP_610223.1	Gene:	PGAP3 / 35570	FlyBaseID:	FBgn0033088	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	NP_001028709.2	Gene:	Pgap3 / 320655	MGIID:	2444461	Length:	320	Species:	Mus musculus

Alignment Length:	327	Identity:	135/327 - (41%)
Similarity:	190/327 - (58%)	Gaps:	17/327 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSSRSLSAIVLLLGALVTACLASNGDRTQFFHNCRQNCERTNCSADGLEIQEQAVKFY--QQSVF 63
            |:.|  :|.:|||...|.....|.|||...:.:|...||..|||.|       |:|.:  :|.::
Mouse     1 MAKR--TAPLLLLTLAVGLAGGSQGDREPVYRDCVLRCEERNCSGD-------ALKHFRSRQPIY 56

  Fly    64 DRLFQWSCADECQYGCMWRTVFAFFERGWPIPQFYGKWPFLRLLGMQEPASVIFSCLNFVVHLRL 128
            ..|..|:|.|:|:|.|||.||..:.:.|..:|||:|||||.|.|.:|||||.:.|.||.:..|.:
Mouse    57 MSLAGWTCRDDCKYECMWFTVGLYLQEGHRVPQFHGKWPFSRFLFIQEPASAVASLLNGLASLVM 121

  Fly   129 LRKFRREVRPDSPCYMLTHIFAVTSLNGWIWSAIFHTRDFPLTELLDYAFAYSIILCSLYVMVMR 193
            |.::|..|...||.|.....||..|||.|.||.:|||||..|||.:||..|.::||.|:|:..:|
Mouse   122 LCRYRASVPASSPMYHTCMAFAWVSLNAWFWSTVFHTRDTDLTEKMDYFCASAVILHSVYLCCVR 186

  Fly   194 ---MLHRYSLFLRGVITLAFLSYYINYFAYLSVGRFNYAFNMMVNVATGVIAAVGWFVWCHFVRT 255
               :.|.......|.:.|..|:.:|   :|||:..|:|.:|||.|||.|::....|.|||...|.
Mouse   187 TVGLQHPSVASAFGALLLLLLTGHI---SYLSLVHFDYGYNMMANVAIGLVNLAWWLVWCLRNRQ 248

  Fly   256 RRPYFRRILRFYILMALAMSLELLDFPPILWILDAHALWHLATIPLASLYYDFMIEDCRTLRKEK 320
            |.|:.||.:...:|:.....||||||||:.|:|||||:||::|||:.:|::.|:.:|...|.||.
Mouse   249 RLPHTRRCMVVVVLLQGLSLLELLDFPPLFWVLDAHAIWHISTIPVHTLFFRFLEDDSLYLLKES 313

  Fly   321 AA 322
            .|
Mouse   314 GA 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PGAP3	NP_610223.1	Per1	65..313	CDD:282000	109/250 (44%)
Pgap3	NP_001028709.2	Per1	54..306	CDD:282000	109/254 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834635
Domainoid	1	1.000	220	1.000	Domainoid score	I2624
eggNOG	1	0.900	-	-		E1_COG5237
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5484
Inparanoid	1	1.050	246	1.000	Inparanoid score	I3262
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59972
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004451
OrthoInspector	1	1.000	-	-		oto93646
orthoMCL	1	0.900	-	-		OOG6_104144
Panther	1	1.100	-	-	LDO	PTHR13148
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R898
SonicParanoid	1	1.000	-	-		X3155
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.790