Protein Alignment Hsepi and Glce

DIOPT Version :10

• Sequence 1: NP_610249.2
• Gene: Hsepi / 35569
• FlyBaseID: FBgn0033087
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_201577.3
• Gene: Glce / 93683
• MGIID: 2136405
• Length: 618
• Species: Mus musculus
• Alignment Length: 628
• Identity: 272/628 - (43%)
• Similarity: 366/628 - (58%)
• Gaps: 73/628 - (11%)

  Fly    44 RLNLKAVLLVLTVAVVVITLGVYMRCAAFSFSPDFVRPLD----------RSARQSS-------- 90
            |:|.| .|:::.....::|:.::.:|:: ..:..|.|.|.          |||...|
Mouse     7 RVNYK-TLIIICALFTLVTVLLWNKCSS-DKAIQFPRHLSSGFRVDGLEKRSAASESNHYANHIA 69

  Fly    91 -----------------------SGGEATAL----HDIECSINQEYTVHCKRDENANEVYVPFSF 128
                                   |.|.:..|    .:|:|.||.|:|:..:|:  .|||::||::
Mouse    70 KQQSEEAFPQEQQKAPPVVGGFNSNGGSKVLGLKYEEIDCLINDEHTIKGRRE--GNEVFLPFTW 132

  Fly   129 LRNYFDVSGAVSTNSNEVAKFNWVHSTAKVNLPRGKYDARGVYMYFENYNVEVRDRVKCISAAEG 193
            :..||||.|.| ...:...:|.:.||.:||...|..|...||:|.||.|||||||||||||..||
Mouse   133 VEKYFDVYGKV-VQYDGYDRFEFSHSYSKVYAQRSPYHPDGVFMSFEGYNVEVRDRVKCISGVEG 196

  Fly   194 VPVSTQWEKRGYFYPTQIAQFALSHYSKNLTEPAPRVRV---LEDGDGN--QMEWSTPKTSNMTR 253
            ||:||||..:|||||.||||:.||||||||||..|.:.|   .||.|.|  ..||:.||...|..
Mouse   197 VPLSTQWGPQGYFYPIQIAQYGLSHYSKNLTEKPPHIEVYETAEDRDRNIRPNEWTVPKGCFMAS 261

  Fly   254 IWHHKFNTSVVQF---ETAPGYEGVISIALNQTLDLLLSVDLLLVTNSSSLMITVQNRDTRHNYS 315
            :.....:|:|.||   ||:.|    :|:.|..|.|.::|.||.|:|| .|:.:.::..:....::
Mouse   262 VADKSRSTNVKQFIAPETSEG----VSLQLGNTKDFIISFDLKLLTN-GSVSVVLETTEKNQLFT 321

  Fly   316 LHYIPADLLLSVQDTNIYYGLGGSALNKWRHITRDLHIDLQKGI-MGDKRS--PLKIRRSDLEVI 377
            :||:....|::.:|.:||||:|  ....|..:||||..||:||: :.:.::  |.||...  :|:
Mouse   322 VHYVSNTQLIAFRDRDIYYGIG--PRTSWSTVTRDLVTDLRKGVGLSNTKAVKPTKIMPK--KVV 382

  Fly   378 SIGFLGLGFFDNITLSTSDHLAHFYDAAEWFVHNQDPKTGGWTNPVRRSL-NGFAELRPGWISAM 441
            .:...|.||.||||:||:.|:|.|:.|::|.|.|||.| |||...|.|.| .||..|.|||.|||
Mouse   383 RLIAKGKGFLDNITISTTAHMAAFFAASDWLVRNQDEK-GGWPIMVTRKLGEGFKSLEPGWYSAM 446

  Fly   442 GQGHAISVLARAYWHSGGDERYLRAAAAGLQPYRVYSRDGGVLAQFMDKFYWYEEYPTTPPSYVL 506
            .||.|||.|.|||..: .|..:|.:|.....||:..|...||.|.||:|..|||||||||.|:||
Mouse   447 AQGQAISTLVRAYLLT-KDYVFLSSALRATAPYKFPSEQHGVKAVFMNKHDWYEEYPTTPSSFVL 510

  Fly   507 NGFIYSLLGLYDLNSTAPGKIAREAGKLFAQGMHSLKKMLLLFDTGSGTSYDLRHLSLGVAPNLA 571
            |||:|||:|||||..||...:.:||..|:.:||.|||.||.|:||||||.|||||..||:|||||
Mouse   511 NGFMYSLIGLYDLKETAGETLGKEARSLYERGMESLKAMLPLYDTGSGTIYDLRHFMLGIAPNLA 575

  Fly   572 RWDYHATHVNQLLLLATIDSDPLIAQTAERWKGYMFGRRAKHN 614
            |||||.||:|||.||:|||..|:..:..:|||.|:.|.|||||
Mouse   576 RWDYHTTHINQLQLLSTIDESPIFKEFVKRWKSYLKGSRAKHN 618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsepi	NP_610249.2	C5-epim_C	415..604	CDD:461978	109/189 (58%)
Glce	NP_201577.3	C5-epim_C	417..608	CDD:461978	111/192 (58%)