Protein Alignment Hsepi and glcea

DIOPT Version :9

• Sequence 1: NP_610249.2
• Gene: Hsepi / 35569
• FlyBaseID: FBgn0033087
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_998015.2
• Gene: glcea / 405776
• ZFINID: ZDB-GENE-040630-9
• Length: 585
• Species: Danio rerio
• Alignment Length: 593
• Identity: 266/593 - (44%)
• Similarity: 365/593 - (61%)
• Gaps: 32/593 - (5%)

  Fly    42 IMRLNLKAVLLVLTVAVVVITLGVYMRCAAFSFSPDFVRPLDRSA----RQSSSGGEA------- 95
            :.|:|.| .|:|:.....:||:.::.:|::....|..||||:.:|    ::..:.|:|
Zfish     5 VARINHK-TLIVICAVFALITILLWNKCSSDKDLPSPVRPLEFAAPTPEKEEENEGQAPEAPPGS 68

  Fly    96 --TALHDIECSINQEYTVHCKRDENANEVYVPFSFLRNYFDVSGAVSTNSNEVAKFNWVHSTAKV 158
              .|...|:|.||::..:..:|:  ..|||:|||::..||||.|.: ...:.:.:|.:.||.::|
Zfish    69 REVAYEQIDCLINEDVLIKGRRE--GGEVYLPFSWVEKYFDVYGRL-VQYDGMERFEFSHSYSRV 130

  Fly   159 NLPRGKYDARGVYMYFENYNVEVRDRVKCISAAEGVPVSTQWEKRGYFYPTQIAQFALSHYSKNL 223
            ...|..|...||:|.||.|||||||||||||..||||:||||..:|||||.||||:.||||||||
Zfish   131 YAQREPYHPDGVFMSFEGYNVEVRDRVKCISGVEGVPISTQWGPQGYFYPIQIAQYGLSHYSKNL 195

  Fly   224 TEPAPRVRV---LEDGDGNQMEWSTPKTSNMTRIWHHKFNTSVVQFETAPGYEGVISIALNQTLD 285
            ||..|.:::   ||:.:|...:|..||...:::|.....:..|..|.||...||| |:.|:...|
Zfish   196 TEKPPDIKIYGMLEEKEGGSSQWDVPKGCTLSKIQDQGRSGFVHHFVTAENSEGV-SLVLDNAKD 259

  Fly   286 LLLSVDLLLVTNSSSLMITVQNRDTRHNYSLHYIPADLLLSVQDTNIYYGLGGSALNKWRHITRD 350
            .:|:.|:..::| .|:.:.::..:....:.:|||.:.||||.:|..:.||:|..|  .|..::||
Zfish   260 FVLTFDVKFISN-GSVSVVLETTEKGPYFIIHYITSPLLLSFKDREVIYGIGPRA--TWSTVSRD 321

  Fly   351 LHIDLQKGIMGDKRSPLKIRR-SDLEVISIGFLGLGFFDNITLSTSDHLAHFYDAAEWFVHNQDP 414
            |..||:||:.......:|..: ....|:.:...|.||..|||:|::.|:|.|:.|::|.:||||
Zfish   322 LVTDLRKGVGLSNTKVVKATKIMPRRVVQLVLKGSGFISNITVSSTAHMAAFFAASDWLLHNQD- 385

  Fly   415 KTGGWTNPVRRSL-NGFAELRPGWISAMGQGHAISVLARAY--WHSGGDERYLRAAAAGLQPYRV 476
            :.|||...|.|.| .||..|.|||.|||.||.|:|.|.|||  .|   :..||.||.....|::.
Zfish   386 EHGGWPIKVTRKLGEGFKSLEPGWYSAMAQGQAMSTLVRAYLVTH---NPSYLGAAIRATSPFKR 447

  Fly   477 YSRDGGVLAQFMDKFYWYEEYPTTPPSYVLNGFIYSLLGLYDLNSTAPGKIAREAGKLFAQGMHS 541
            .....||.|.||:||.|||||||||.|:|||||||||:||||:..||..|:.||||.||:||:.|
Zfish   448 TPEQHGVKATFMNKFDWYEEYPTTPSSFVLNGFIYSLIGLYDVAETAGNKLGREAGILFSQGLES 512

  Fly   542 LKKMLLLFDTGSGTSYDLRHLSLGVAPNLARWDYHATHVNQLLLLATIDSDPLIAQTAERWKGYM 606
            ||.||.||||||||.|||||.:|||||||||||||.||:|||.|||:||..|:.....:|||.|:
Zfish   513 LKAMLPLFDTGSGTVYDLRHFTLGVAPNLARWDYHTTHINQLQLLASIDGAPIFRDYVKRWKTYL 577

  Fly   607 FGRRAKHN 614
            .|.|||||
Zfish   578 KGGRAKHN 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsepi	NP_610249.2	C5-epim_C	415..604	CDD:284151	114/191 (60%)
glcea	NP_998015.2	C5-epim_C	384..575	CDD:284151	116/194 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582090
Domainoid	1	1.000	246	1.000	Domainoid score	I2131
eggNOG	1	0.900	-	-		E1_KOG3760
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	479	1.000	Inparanoid score	I1435
OMA	1	1.010	-	-		QHG49344
OrthoDB	1	1.010	-	-		D257141at33208
OrthoFinder	1	1.000	-	-		FOG0006406
OrthoInspector	1	1.000	-	-		otm25555
orthoMCL	1	0.900	-	-		OOG6_106888
Panther	1	1.100	-	-	O	PTHR13174
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2543
SonicParanoid	1	1.000	-	-		X4669
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.800