Protein Alignment Hsepi and Hsepi

DIOPT Version :10

• Sequence 1: NP_610249.2
• Gene: Hsepi / 35569
• FlyBaseID: FBgn0033087
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: XP_061500369.1
• Gene: Hsepi / 1276368
• VectorBaseID: AGAMI1_002745
• Length: 592
• Species: Anopheles gambiae
• Alignment Length: 589
• Identity: 344/589 - (58%)
• Similarity: 428/589 - (72%)
• Gaps: 19/589 - (3%)

  Fly    34 QREPLVFFIMRLNLKAVLLVLTVAVVVITLGVYMRC-AAFSFSPDFVRPLDRSARQSSSGGEATA 97
            |:......|||||||.:|:.|.|.|.:||..::..| ....|.|.:.:....||   .|..|.|
Mosquito    15 QKARFFLVIMRLNLKFLLISLCVTVALITFALWANCGVGHGFVPKWPQHHGDSA---DSPFEQT- 75

  Fly    98 LHDIECSINQEYTVHCKRDENANEVYVPFSFLRNYFDVSGAVSTNSNEVAKFNWVHSTAKVNLPR 162
             .:|:|.|||||.:.|:::  ..|||:|||||:.||||.|:::..... .:|:|.||..|||.|:
Mosquito    76 -EEIDCIINQEYAIGCRKE--GEEVYLPFSFLQKYFDVYGSLNVVDGS-RRFDWTHSYGKVNYPK 136

  Fly   163 GKYDARGVYMYFENYNVEVRDRVKCISAAEGVPVSTQWEKRGYFYPTQIAQFALSHYSKNLTEPA 227
            |.||.||::|||||||||:|||||||||.:|||:|||||.:||||.||||||.|||||||||||.
Mosquito   137 GAYDPRGIFMYFENYNVEMRDRVKCISAIDGVPISTQWESQGYFYATQIAQFGLSHYSKNLTEPE 201

  Fly   228 PRVRVLEDGDGNQMEWSTPKTSNMTR-IWHHKFNT-SVVQFETAPGYEGVISIALNQTLDLLLSV 290
            ||.:.:|||:.....|..||.|:|.| |...:... :|:.|.|...::..:.:.::..|||:|||
Mosquito   202 PRRKTVEDGERETATWIVPKGSSMNRTIDRARAGAGAVLSFSTGKSFDTAVVLPMDHVLDLVLSV 266

  Fly   291 DLLLVTNSSSLMITVQNRDTRHNYSLHYIPADLLLSVQDTNIYYGLGGSALNKWRHITRDLHIDL 355
            |:||..| |:|.:|:|||:|:..|.::||.||||:.|||.|||||:|.:....|:|:||||.:||
Mosquito   267 DVLLKPN-STLCVTLQNRETQKLYHVYYILADLLIGVQDENIYYGIGLNCTGGWKHLTRDLFVDL 330

  Fly   356 QKGI----MGDKRSPLKIRRSDLEVISIGFLGLGFFDNITLSTSDHLAHFYDAAEWFVHNQDPKT 416
            |||:    ..|||.  |:||::|:|:.|..||.|..||:|||||:|::||||||||.:.:|||.|
Mosquito   331 QKGLPQYASTDKRR--KMRRTELKVVEISLLGNGSIDNLTLSTSEHISHFYDAAEWLIRHQDPST 393

  Fly   417 GGWTNPVRRSL-NGFAELRPGWISAMGQGHAISVLARAYWHSGGDERYLRAAAAGLQPYRVYSRD 480
            |||..||||.| :||.||..||.|||.||||||:|||||:||.||:||||||..||:.:|:.|..
Mosquito   394 GGWPIPVRRKLGSGFGELARGWYSAMAQGHAISLLARAYYHSKGDKRYLRAALDGLKLFRIPSYQ 458

  Fly   481 GGVLAQFMDKFYWYEEYPTTPPSYVLNGFIYSLLGLYDLNSTAPGKIAREAGKLFAQGMHSLKKM 545
            |||||.|:.|:.|||||||||.|:||||||||||||||||||||...:.||..||.|||.|||||
Mosquito   459 GGVLATFLGKYAWYEEYPTTPHSFVLNGFIYSLLGLYDLNSTAPANQSNEAAVLFEQGMASLKKM 523

  Fly   546 LLLFDTGSGTSYDLRHLSLGVAPNLARWDYHATHVNQLLLLATIDSDPLIAQTAERWKGYMFGRR 610
            |||:||||||||||||.:||:||||||||||||||||||||||||.||||:|||||||.||.|:|
Mosquito   524 LLLYDTGSGTSYDLRHFTLGIAPNLARWDYHATHVNQLLLLATIDPDPLISQTAERWKNYMVGKR 588

  Fly   611 AKHN 614
            |.||
Mosquito   589 APHN 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsepi	NP_610249.2	C5-epim_C	415..604	CDD:461978	143/189 (76%)
Hsepi	XP_061500369.1	None