DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dpit47 and TOM70

DIOPT Version :10

Sequence 1:NP_525106.2 Gene:Dpit47 / 35565 FlyBaseID:FBgn0266518 Length:396 Species:Drosophila melanogaster
Sequence 2:NP_014278.3 Gene:TOM70 / 855602 SGDID:S000005065 Length:617 Species:Saccharomyces cerevisiae


Alignment Length:424 Identity:85/424 - (20%)
Similarity:139/424 - (32%) Gaps:167/424 - (39%)


- Green bases have known domain annotations that are detailed below.


  Fly    77 KLKYDPEENTRDELALNYKEDGNFYMKHKKFRMAIYSFTEGIKTKTDNPDVLAVLYNNRSAAHFF 141
            |..:..||  :|:.||..|:.||.:.::||:..||..:...::.|.|     .|.|:|.||.:..
Yeast    87 KANFTAEE--KDKYALALKDKGNQFFRNKKYDDAIKYYNWALELKED-----PVFYSNLSACYVS 144

  Fly   142 IKNYRSSLSDAQRALFYKPDYTKARWRSAQCAYELERF--------------DLCTQMCEELLE- 191
            :.:.:..:..:.:||..||||:|...|.|.....|.:|              |......|.:|| 
Yeast   145 VGDLKKVVEMSTKALELKPDYSKVLLRRASANEGLGKFADAMFDLSVLSLNGDFNDASIEPMLER 209

  Fly   192 --------------VDVDNEVAI--------ALLHKNKMKKL---------------EIERNQRK 219
                          .|:|...|.        |...|:|.:.|               |:......
Yeast   210 NLNKQAMSKLKEKFGDIDTATATPTELSTQPAKERKDKQENLPSVTSMASFFGIFKPELTFANYD 274

  Fly   220 EAAEA------------KRRLTRFHRLRDAIEQRAIKFDDQ--KVGKKDVLSEELLYP------- 263
            |:.||            ||....:.:..::..:.|..|::|  |..:.:.|.|:|...       
Yeast   275 ESNEADKELMNGLSNLYKRSPESYDKADESFTKAARLFEEQLDKNNEDEKLKEKLAISLEHTGIF 339

  Fly   264 KFL---PLEDH--------------------------------------PVHLDEDGSTL----- 282
            |||   ||..|                                      .:.||.:.|::     
Yeast   340 KFLKNDPLGAHEDIKKAIELFPRVNSYIYMALIMADRNDSTEYYNYFDKALKLDSNNSSVYYHRG 404

  Fly   283 --------------------------IWP----AAFSYP-------EFLYSDFYQQLPETTTMRD 310
                                      |:|    |..:|.       |.|:|:..::.||...:.:
Yeast   405 QMNFILQNYDQAGKDFDKAKELDPENIFPYIQLACLAYRENKFDDCETLFSEAKRKFPEAPEVPN 469

  Fly   311 CLATLLTEKLPYDKA-HNYRLGNVHVYYENRKVG 343
            ..|.:||:|..:||| ..|.|.   :..||:..|
Yeast   470 FFAEILTDKNDFDKALKQYDLA---IELENKLDG 500

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dpit47NP_525106.2 3a0801s09 84..>179 CDD:273380 28/94 (30%)
TPR repeat 91..119 CDD:276809 9/27 (33%)
TPR repeat 124..158 CDD:276809 7/33 (21%)
TPR repeat 163..191 CDD:276809 7/41 (17%)
TPR repeat 197..227 CDD:276809 10/64 (16%)
CTWD_Cns1 232..387 CDD:439174 37/205 (18%)
TOM70NP_014278.3 3a0801s09 1..614 CDD:273380 85/424 (20%)
TPR repeat 99..127 CDD:276809 9/27 (33%)
TPR repeat 131..161 CDD:276809 8/34 (24%)
TPR repeat 166..189 CDD:276809 5/22 (23%)
TPR repeat 330..358 CDD:276809 6/27 (22%)
TPR repeat 363..391 CDD:276809 0/27 (0%)
TPR repeat 396..426 CDD:276809 1/29 (3%)
TPR repeat 431..459 CDD:276809 7/27 (26%)
TPR repeat 465..493 CDD:276809 9/30 (30%)
TPR repeat 498..537 CDD:276809 1/3 (33%)
TPR repeat 542..567 CDD:276809
Blue background indicates that the domain is not in the aligned region.

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