DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dpit47 and Sgt

DIOPT Version :9

Sequence 1:	NP_001260729.1	Gene:	Dpit47 / 35565	FlyBaseID:	FBgn0266518	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	NP_001246058.1	Gene:	Sgt / 35052	FlyBaseID:	FBgn0032640	Length:	331	Species:	Drosophila melanogaster

Alignment Length:	191	Identity:	49/191 - (25%)
Similarity:	87/191 - (45%)	Gaps:	22/191 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 MFEGLQKL--KYDPEENTRDELALNYKEDGNFYMKHKKFRMAIYSFTEGIKTKTDNPDVLAVLYN 133
            |||..|.|  :.:||...   ||.:.|.:||..||..|:..|:..:...|.....||    :.|.
  Fly    97 MFELFQSLYTERNPESLA---LAESIKNEGNRLMKENKYNEALLQYNRAIAFDPKNP----IFYC 154

  Fly   134 NRSAAHFFIKNYRSSLSDAQRALFYKPDYTKARWRSAQCAYELERFDLCTQMCEELLEVDVDNEV 198
            ||:|||..:.....:::|.:.||.|..:|:||..|.......:..|:...|...:.:|::.||||
  Fly   155 NRAAAHIRLGENERAVTDCKSALVYNNNYSKAYCRLGVAYSNMGNFEKAEQAYAKAIELEPDNEV 219

  Fly   199 AIALLHKNKMKKLEIERNQRKEAAEAKRRLTRFHRLRDAIEQRAIK--FDDQKVGKKDVLS 257
                 :|:.::.....|||..:....:..|.      :.:.|..::  |::.::..:.:||
  Fly   220 -----YKSNLEAARNARNQPPQTGRLREDLI------NMLSQPMVRNLFNNAEIDVEQLLS 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dpit47	NP_001260729.1	3a0801s09	84..>179	CDD:273380	26/94 (28%)
		TPR repeat	91..119	CDD:276809	8/27 (30%)
		TPR repeat	124..158	CDD:276809	11/33 (33%)
		TPR repeat	163..191	CDD:276809	5/27 (19%)
		TPR repeat	197..227	CDD:276809	6/29 (21%)
Sgt	NP_001246058.1	SGTA_dimer	9..>48	CDD:293154
		TPR_11	116..177	CDD:290150	18/64 (28%)
		TPR_2	116..149	CDD:285020	9/32 (28%)
		TPR repeat	116..144	CDD:276809	8/27 (30%)
		TPR_17	139..170	CDD:290167	9/34 (26%)
		TPR repeat	149..179	CDD:276809	11/33 (33%)
		TPR_16	156..218	CDD:290168	16/61 (26%)
		TPR_1	184..217	CDD:278916	6/32 (19%)
		TPR repeat	184..212	CDD:276809	5/27 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462411
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840