DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fmo-2 and AT1G63370

DIOPT Version :9

Sequence 1:	NP_610217.1	Gene:	Fmo-2 / 35561	FlyBaseID:	FBgn0033079	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	NP_176526.1	Gene:	AT1G63370 / 842643	AraportID:	AT1G63370	Length:	450	Species:	Arabidopsis thaliana

Alignment Length:	447	Identity:	138/447 - (30%)
Similarity:	222/447 - (49%)	Gaps:	55/447 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 VCVIGAGTAGLCALKNSLEAGLDAVAYERGTEIGGTWIFSEEMPKDEY------DEVHSSMYEGL 69
            |.|||||.|||.|.:.....|...|.:|:..::|||||:::|:..|..      ..||||:|..|
plant    13 VAVIGAGPAGLVAARELRREGHSVVVFEKQKQVGGTWIYTDEVESDPLSVDPTRSVVHSSVYRSL 77

  Fly    70 RTNLPKEVMGYPDYSYPDDITES--------FITSNQVLEFLRSYAEHFKLKAHIKLQHEVIRVR 126
            |.|..:|..||.|:.:   :..|        |.:..:||.:|:.:|:.|.::..::.:.||::|.
plant    78 RINGTRECTGYRDFPF---VVRSGVSRDRRRFPSHGEVLAYLKDFAKEFGIEEMVRFETEVVKVS 139

  Fly   127 PRLDD----WEVYVWDHSTDTCDPVYYDFVYVCNGHYTEPDLPEVEGLDLFEGNKMHSHLYRKAD 187
            |..::    |.:...:..........||.|.||||||.||.|.::.|:..:.|.:||||.||..:
plant   140 PAAEEGIGKWRIESTEKEKKVRRDEIYDAVVVCNGHYVEPRLAQIPGISSWPGKEMHSHNYRIPE 204

  Fly   188 KFKDARVLIIGAGPSGMDITNHVRLAAKQVFLSHHLSTTPNTA--FM-----GNVTQKPDVKRFT 245
            .|:|...::||...|..||:..:...||:|    |::...|.|  |:     .|:.....::...
plant   205 PFRDKVAVLIGNSSSAEDISRDIARVAKEV----HVACRSNPADTFIKQTGYNNLWTHSMIESVH 265

  Fly   246 KDGA-VFTDGSTESFDHVMFCTGYKYTFPCLSTDVGVQVIDNFVQPLWKHCI-NINHPTMAFVGL 308
            :||: |:.:|.|.|.|.:|.||||||.||.|.|:..|.|.||.|.||:|... ....|.::|:|:
plant   266 EDGSVVYQNGKTISVDIIMHCTGYKYHFPFLDTNGIVTVDDNRVGPLYKDVFPPAFAPWLSFIGI 330

  Fly   309 PFNVIPTHIFDMQVRFTLKFFTGQRKFPSREQMIADLE--------QEIGERWGCGVRNQKKAHQ 365
            |:.|:|..:|::|.::.....:|:...||:|.|:.:::        |.|.:|:         .|:
plant   331 PWQVLPFPMFELQSKWIAGVLSGRIPLPSKEDMMIEIKTFYSTLEVQGIPKRY---------THR 386

  Fly   366 MGERQFVYYNELASIAGIENIKPVIHKLMKDCGKKYIFELDTYRSNKYTILDDENFL 422
            ||..||.|.|.|||..|....:....::....|.:.....:|||..    .||.:.:
plant   387 MGNTQFEYDNWLASQCGCSETEEWRKEMCLANGVRKEAHPETYRDE----WDDHHLV 439

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fmo-2	NP_610217.1	NADB_Rossmann	12..214	CDD:304358	70/219 (32%)
AT1G63370	NP_176526.1	PLN02172	1..447	CDD:215116	138/447 (31%)
AT1G63370	NP_176526.1	NAD_binding_8	15..>56	CDD:290186	18/40 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	150	1.000	Domainoid score	I1415
eggNOG	1	0.900	-	-		E1_COG2072
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	225	1.000	Inparanoid score	I1172
OMA	1	1.010	-	-		QHG55225
OrthoDB	1	1.010	-	-		D405736at2759
OrthoFinder	1	1.000	-	-		FOG0000093
OrthoInspector	1	1.000	-	-		mtm1034
orthoMCL	1	0.900	-	-		OOG6_100150
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X69
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.740