DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fmo-2 and AT1G62600

DIOPT Version :9

Sequence 1:	NP_610217.1	Gene:	Fmo-2 / 35561	FlyBaseID:	FBgn0033079	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	NP_176448.1	Gene:	AT1G62600 / 842557	AraportID:	AT1G62600	Length:	452	Species:	Arabidopsis thaliana

Alignment Length:	451	Identity:	147/451 - (32%)
Similarity:	226/451 - (50%)	Gaps:	51/451 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 VDKRRVCVIGAGTAGLCALKNSLEAGLDAVAYERGTEIGGTWIFSEEMPKDEY------DEVHSS 64
            :....|.|||||.|||.|.:.....|...|.:||..::|||||:::.:..|..      ..||||
plant     8 IRSHHVAVIGAGAAGLVAARELRREGHSVVVFERQKQVGGTWIYTDHIEPDPLSVDPTRSVVHSS 72

  Fly    65 MYEGLRTNLPKEVMGYPDYSY--PDDITES-----FITSNQVLEFLRSYAEHFKLKAHIKLQHEV 122
            :|..||||||:|.|||.|:.:  ..|::||     |.:..:||.:|:.:|:.|.::..|:....|
plant    73 VYGSLRTNLPRECMGYRDFPFVIRSDVSESRDPRRFPSHGEVLAYLQDFAKEFAIEEMIRFDTAV 137

  Fly   123 IRVRPRLDD----WEVYVWDHSTDTCDPVYYDFVYVCNGHYTEPDLPEVEGLDLFEGNKMHSHLY 183
            ::|.|..::    |.:...:..........||.|.||||||.||...|:.|:..:.|.:||||.|
plant   138 VKVAPAAEEGSGKWRIESTEKEKKVLRDEIYDAVVVCNGHYIEPRHAEIPGISSWPGKEMHSHNY 202

  Fly   184 RKADKFKDARVLIIGAGPSGMDITNHVRLAAKQVFLSHHLSTTPNTA-------FMGNVTQKPDV 241
            |..:.|:|..|::||...|..||:..:...||:|    |::...|.|       ...|:.....:
plant   203 RIPEPFRDQVVVLIGNSASADDISRDIARVAKEV----HVACRSNAADTYIERPGYSNLWMHSMI 263

  Fly   242 KRFTKDGA-VFTDGSTESFDHVMFCTGYKYTFPCLSTDVGVQVIDNFVQPLWKHCIN-INHPTMA 304
            :...:||: ||.:|.|.|.|.:|.||||||.||.|.|:..|.|.||.|.||:|...: ...|.::
plant   264 ESVHEDGSVVFQNGKTISVDVIMHCTGYKYHFPFLETNGNVTVDDNRVGPLYKDVFSPAFAPWLS 328

  Fly   305 FVGLPFNVIPTHIFDMQVRFTLKFFTGQRKFPSREQMIADLE--------QEIGERWGCGVRNQK 361
            |||:|:.|:|..:|::|.::.....:|:...||:|.|:.:::        |.|.:|:
plant   329 FVGIPWKVVPFPMFELQSKWIAGVLSGRIPLPSKEDMMMEIKTLYSTLDAQGIAKRY-------- 385

  Fly   362 KAHQMGERQFVYYNELASIAGIENIKPVIHKLMKDCGKKYIFELDTYRSNKYTILDDENFL 422
             .||||..||.|.:.|||..|....:....::....|.|.....:|||..    .||.:.:
plant   386 -THQMGISQFEYNSWLASQCGCSETEEWRKEMYFATGVKKRAHPETYRDE----WDDHHLV 441

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fmo-2	NP_610217.1	NADB_Rossmann	12..214	CDD:304358	77/218 (35%)
AT1G62600	NP_176448.1	PLN02172	1..449	CDD:215116	147/451 (33%)
AT1G62600	NP_176448.1	NADB_Rossmann	35..242	CDD:304358	71/210 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	150	1.000	Domainoid score	I1415
eggNOG	1	0.900	-	-		E1_COG2072
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	225	1.000	Inparanoid score	I1172
OMA	1	1.010	-	-		QHG55225
OrthoDB	1	1.010	-	-		D405736at2759
OrthoFinder	1	1.000	-	-		FOG0000093
OrthoInspector	1	1.000	-	-		mtm1034
orthoMCL	1	0.900	-	-		OOG6_100150
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X69
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.740