DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Fmo-2 and NOGC1

DIOPT Version :9

Sequence 1:	NP_610217.1	Gene:	Fmo-2 / 35561	FlyBaseID:	FBgn0033079	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	NP_176446.1	Gene:	NOGC1 / 842555	AraportID:	AT1G62580	Length:	497	Species:	Arabidopsis thaliana

Alignment Length:	475	Identity:	147/475 - (30%)
Similarity:	222/475 - (46%)	Gaps:	79/475 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 VCVIGAGTAGLCALKNSLEAGLDAVAYERGTEIGGTWIFSEEMPKDEYD------EVHSSMYEGL 69
            |.|||||.|||.|.:.....|...|.:|||..|||.|.::..:..|...      .:|||:|..|
plant    14 VAVIGAGAAGLVAARELRREGHSVVVFERGNHIGGVWAYTPNVEPDPLSIDPTRPVIHSSLYSSL 78

  Fly    70 RTNLPKEVMGYPDYSYPDDITES------FITSNQVLEFLRSYAEHFKLKAHIKLQHEVIRVRPR 128
            ||.:|:|.||:.|:.:...:...      ....::||.:||.:...||::..|:.:.||:||...
plant    79 RTIIPQECMGFTDFPFSTRLENGSRDPRRHPGHSEVLAYLRDFVREFKIEEMIRFETEVVRVEQA 143

  Fly   129 LDD---WEVYVWDHSTDTCDPVYYDFVYVCNGHYTEPD---LPEVE---------GLDLFEGNKM 178
            .::   |.|...:.. |..|.: ||.|.|||||||||.   :|..:         |:|.:.|.::
plant   144 GENPKKWRVKSRNFG-DISDEI-YDAVVVCNGHYTEPRHALIPGNKINHSFSIGLGIDTWPGKQI 206

  Fly   179 HSHLYRKADKFKDARVLIIGAGPSGMDITNHVRLAAKQVFLSHHLSTTPNT----AFMGNVTQKP 239
            |||.||..::.||..|::||:..||:||:..:....|:|.:|.. ||.|.|    ....|:....
plant   207 HSHNYRVPEQVKDQVVVVIGSSVSGVDISRDIANVTKEVHISSR-STKPETYEKLPGYDNLWLHS 270

  Fly   240 DVKRFTKDGA-VFTDGSTESFDHVMFCTGYKYTFPCLSTDVGVQVIDNFVQPLWKHCI-NINHPT 302
            :::...:||: ||.:|.|...|.:|.||||||.||.|.|...|.|.||.|.||:||.. ....|.
plant   271 NIETVREDGSVVFKNGKTVYADTIMHCTGYKYYFPFLDTKGEVTVEDNRVGPLYKHVFPPALSPG 335

  Fly   303 MAFVGLPFN---------------------VIPTHIFDMQVRFTLKFFTGQRKFPSREQM----- 341
            ::|:|||:.                     |||..:|::|.::......|:...||:|:|
plant   336 LSFIGLPWQNMKLQTLDVNELIGQCFGYLLVIPFPMFELQSKWVAAVLAGRVSLPSQEEMEDTKM 400

  Fly   342 -IADLEQE-IGERWGCGVRNQKKAHQMGE--RQFVYYNELASIAGIENIKPVIHKLMKDCGKKYI 402
             ...||.. |.:|:         .|.|.|  .||||.|.||.......|:....::.....|:..
plant   401 FYLKLEASCIPKRY---------THLMAELDSQFVYNNWLADQCDYPRIEKWREQMFYKVFKRIQ 456

  Fly   403 FELDTYRSNKYTILDDENFL 422
            .:..||:.:    .||::.:
plant   457 SQASTYKDD----WDDDHLI 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fmo-2	NP_610217.1	NADB_Rossmann	12..214	CDD:304358	76/228 (33%)
NOGC1	NP_176446.1	PLN02172	1..492	CDD:215116	147/475 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	150	1.000	Domainoid score	I1415
eggNOG	1	0.900	-	-		E1_COG2072
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	225	1.000	Inparanoid score	I1172
OMA	1	1.010	-	-		QHG55225
OrthoDB	1	1.010	-	-		D405736at2759
OrthoFinder	1	1.000	-	-		FOG0000093
OrthoInspector	1	1.000	-	-		mtm1034
orthoMCL	1	0.900	-	-		OOG6_100150
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X69
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.740