DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fmo-2 and FMO GS-OX3

DIOPT Version :9

Sequence 1:	NP_610217.1	Gene:	Fmo-2 / 35561	FlyBaseID:	FBgn0033079	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	NP_176444.1	Gene:	FMO GS-OX3 / 842553	AraportID:	AT1G62560	Length:	462	Species:	Arabidopsis thaliana

Alignment Length:	464	Identity:	139/464 - (29%)
Similarity:	234/464 - (50%)	Gaps:	48/464 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KTSVDKRRVCVIGAGTAGLCALKNSLEAGLDAVAYERGTEIGGTWIFSEEMPKDEYD-------- 59
            :..:..:.|.|||||.|||...:.....|...|.:||..::||.|:::   ||.:.|
plant     5 QNQITSKHVAVIGAGPAGLITSRELRREGHSVVVFEREKQVGGLWVYT---PKSDSDPLSLDPTR 66

  Fly    60 -EVHSSMYEGLRTNLPKEVMGYPDYSY-P--DDITES---FITSNQVLEFLRSYAEHFKLKAHIK 117
             :||||:||.||||:|:|.||..|:.: |  ||.:..   :....:||.:::.:|..||::..|:
plant    67 SKVHSSIYESLRTNVPRESMGVRDFPFLPRFDDESRDARRYPNHREVLAYIQDFAREFKIEEMIR 131

  Fly   118 LQHEVIRVRPRLD--DWEVYVWDHSTDTCDPVYYDFVYVCNGHYTEPDLPEVEGLDLFEGNKMHS 180
            .:.||:||.| :|  :|.|.. .:|....:...||.|.|||||||||::..:.|:..:.|.::||
plant   132 FETEVVRVEP-VDNGNWRVQS-KNSGGFLEDEIYDAVVVCNGHYTEPNIAHIPGIKSWPGKQIHS 194

  Fly   181 HLYRKADKFKDARVLIIGAGPSGMDITNHVRLAAKQVFLSHHLSTTPNT-----AFMGNVTQKPD 240
            |.||..|.|::..|::||...||.||:..:...||:|.::.. :..|:|     ....|:....:
plant   195 HNYRVPDPFENEVVVVIGNFASGADISRDIAKVAKEVHIASR-AREPHTYEKISVPQNNLWMHSE 258

  Fly   241 VKRFTKDGA-VFTDGSTESFDHVMFCTGYKYTFPCLSTDVGVQVIDNFVQPLWKHCI-NINHPTM 303
            :....:||: ||.:|.....|.:::||||||.||.|.|:..:::.:..|:||:||.. ....|.:
plant   259 IDTTHEDGSIVFKNGKVIFADSIVYCTGYKYNFPFLETNGYLRIDEKRVEPLYKHVFPPALAPGL 323

  Fly   304 AFVGLPFNVIPTHIFDMQVRFTLKFFTGQRKFPSREQMIADLEQEIGERWGCGVRNQKKAHQMGE 368
            ||||||...|...:|::|.::.....:|:...||.::|:.|:..........|: .::..|.:|.
plant   324 AFVGLPAMGIVFVMFEIQSKWVAAVLSGRVTLPSTDKMMEDINAWYASLDALGI-PKRHTHTIGR 387

  Fly   369 RQFVYYNELASIAGIENIKPVIHKLMKDCGKKYIFELDTYRS-----------------NKYTIL 416
            .|..|.|.:|..:|.|.::....:.:.....:.:...:|||.                 .|...:
plant   388 IQSEYLNWVAKESGCELVERWRGQEVDGGYLRLVAHPETYRDEWDDDELIEEAYNDFSRKKLISV 452

  Fly   417 DDENFLKNG 425
            |...:|:||
plant   453 DPSYYLENG 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fmo-2	NP_610217.1	NADB_Rossmann	12..214	CDD:304358	79/218 (36%)
FMO GS-OX3	NP_176444.1	PLN02172	1..462	CDD:215116	139/464 (30%)
FMO GS-OX3	NP_176444.1	NADB_Rossmann	14..238	CDD:304358	82/229 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	150	1.000	Domainoid score	I1415
eggNOG	1	0.900	-	-		E1_COG2072
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	225	1.000	Inparanoid score	I1172
OMA	1	1.010	-	-		QHG55225
OrthoDB	1	1.010	-	-		D405736at2759
OrthoFinder	1	1.000	-	-		FOG0000093
OrthoInspector	1	1.000	-	-		mtm1034
orthoMCL	1	0.900	-	-		OOG6_100150
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X69
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.740