DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fmo-2 and AT1G12160

DIOPT Version :9

Sequence 1:	NP_610217.1	Gene:	Fmo-2 / 35561	FlyBaseID:	FBgn0033079	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	NP_172680.1	Gene:	AT1G12160 / 837768	AraportID:	AT1G12160	Length:	468	Species:	Arabidopsis thaliana

Alignment Length:	458	Identity:	144/458 - (31%)
Similarity:	228/458 - (49%)	Gaps:	59/458 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 RRVCVIGAGTAGLCALKNSLEAGLDAVAYERGTEIGGTWIFSEEMPKDEYDE------VHSSMYE 67
            |.|.|||.|.|||.|::.....|...:.:||...:||.|::::.:..|....      ||||:|:
plant    10 RHVAVIGLGAAGLVAVRELRREGHTVIGFEREKHVGGLWVYTDRVDSDSVSVDPDRTIVHSSIYQ 74

  Fly    68 GLRTNLPKEVMGYPDY------------SYPDDITESFITSNQVLEFLRSYAEHFKLKAHIKLQH 120
            .||||||:|.|||.|:            .|||        ..:||.:|:.:|:.||::..|:.:.
plant    75 SLRTNLPRECMGYSDFPFVTRSSDGDPRRYPD--------HREVLMYLQDFAKEFKIEDMIRFET 131

  Fly   121 EVIRVRPRLDD---WEVYVWDHSTDTCDPVYYDFVYVCNGHYTEPDLPEVEGLDLFEGNKMHSHL 182
            ||:.|.|..::   |.|. :..|........:|.|.|||||:|||.|..:.|::.:.|.::|||.
plant   132 EVLCVEPSPENNRKWRVQ-FKSSNGVSGEEIFDAVVVCNGHFTEPRLAHIPGIESWPGKQIHSHN 195

  Fly   183 YRKADKFKDARVLIIGAGPSGMDITNHVRLAAKQVFLSHHLSTTPNTAFMGNVTQKPDVKRFTKD 247
            ||..|.|||..|::||:..||.||:..:...||:|.:|..:..:.:.....|:...|.:.|..:|
plant   196 YRIPDPFKDEVVIVIGSQASGNDISTDIATIAKEVHISSKMVASDSYGCYDNLRIHPTIYRARED 260

  Fly   248 GA-VFTDGSTESFDHVMFCTGYKYTFPCLSTDVGVQVIDNFVQPLWKHCININHPTMA----FVG 307
            |: ||.:|.....|.::.||||||.||.|.|...|.|.||.|.||:||   :..|.:|    |:|
plant   261 GSVVFRNGKVVFADAIVHCTGYKYHFPFLKTSGYVTVEDNRVGPLYKH---VFPPALAPGISFIG 322

  Fly   308 LPFNVIPTHIFDMQVRFTLKFFTGQRKFPSREQMIAD-------LEQ-EIGERWGCGVRNQKKAH 364
            |||..:...:|::|.::.....:|:.|.|:.::|:.:       ||. .|.:|:...:.:.:...
plant   323 LPFMGLQFFMFEIQSKWVASVLSGRVKLPAEDKMMEEAVAFYSKLEDLGIPKRYTHFLTDPRGNP 387

  Fly   365 QMGE---------RQFVYYNELASIAGIENIKPVIHKLMKDCGKKYIFELDTYRSNKYTILDDEN 420
            .:|.         .|..|:|.:|...|..:|:....:|.....||..|..|:||..    .||:.
plant   388 MLGTFKPEDAVVISQSDYFNWIAKQCGCTSIERWRERLYNVAIKKVFFGGDSYRDR----WDDDQ 448

  Fly   421 FLK 423
            .::
plant   449 LIE 451

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fmo-2	NP_610217.1	NADB_Rossmann	12..214	CDD:304358	77/222 (35%)
AT1G12160	NP_172680.1	PLN02172	9..461	CDD:215116	144/458 (31%)
		NAD_binding_8	14..>55	CDD:290186	14/40 (35%)
		P-loop_NTPase	171..>250	CDD:304359	28/78 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	150	1.000	Domainoid score	I1415
eggNOG	1	0.900	-	-		E1_COG2072
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	225	1.000	Inparanoid score	I1172
OMA	1	1.010	-	-		QHG55225
OrthoDB	1	1.010	-	-		D405736at2759
OrthoFinder	1	1.000	-	-		FOG0000093
OrthoInspector	1	1.000	-	-		mtm1034
orthoMCL	1	0.900	-	-		OOG6_100150
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X69
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.740