DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fmo-2 and AT5G45180

DIOPT Version :9

Sequence 1:	NP_610217.1	Gene:	Fmo-2 / 35561	FlyBaseID:	FBgn0033079	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	NP_199331.2	Gene:	AT5G45180 / 834554	AraportID:	AT5G45180	Length:	459	Species:	Arabidopsis thaliana

Alignment Length:	490	Identity:	113/490 - (23%)
Similarity:	178/490 - (36%)	Gaps:	153/490 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 RVCVIGAGTAGLCALKNSLEAGLDAVAYERGTEIGGTWIFSEEMPKDEYDEVHSSMYEGLRTNLP 74
            ||.:||||.:||.|.|:.  |......:|....|||.|              ....||  .|.|.
plant    12 RVAIIGAGVSGLAAAKHL--ARHHPQVFEASDSIGGVW--------------RKCTYE--TTKLQ 58

  Fly    75 KEVMGY--PDYSYPDDITESFITSNQVLEFLRSYAEHFKLKAHIKLQHEVIRVR-------PRLD 130
            ...:.|  .|:.:|:....||.|...||::|.:||:||.|...||...:|:.:|       .::.
plant    59 SVRVSYELSDFLWPNRGESSFPTYVDVLDYLEAYAKHFNLVKFIKFNSKVVELRFIGDGKTLQMG 123

  Fly   131 DWEVY--------VWDHSTDTCDPVY----YDFVYVCNGHYTE----PDLPEVEGLDLFEGNKMH 179
            |...|        ||:.:.:|.|...    :::|.||.|.|.:    |..|..:|.::|:|..:|
plant   124 DLGAYGNLLPGKPVWEVAVNTGDGDIQWHAFEYVVVCAGKYGDVPRTPTFPVKKGPEIFKGKVLH 188

  Fly   180 SHLYRKADKFKDARVL------IIGAGPSGMDITNHVRLA--------------AKQVFLSHHLS 224
            |..|.|..|.|.:::|      :||...|.:|:.....||              .....:.|:..
plant   189 SMDYSKLQKEKASQLLHGKKVAVIGFKKSAIDLALESALANQGKEGKTCTMVVRTPHWVIPHYWR 253

  Fly   225 TT---------------------PNTAF--------MGNVTQK------PDVKRFTK-------- 246
            .|                     |:.||        |..|.:|      ..:.||.:
plant   254 ATVSKFIESYVLWKLPLEKYGLKPDHAFEEDYASCQMALVPEKFFEEADKGMIRFKRTTNWWFYD 318

  Fly   247 DGAVFTDGSTESFDHVMFCTGYKYTFPCLSTDVGVQVIDNFV--------------QPLWKHCIN 297
            :|..|.||:|...|.|:..|||.          |::.:...|              .||::..|:
plant   319 EGIEFEDGTTLEADVVILATGYD----------GMKKLKAIVPEPFRSWLEFPWGIMPLYRGTIH 373

  Fly   298 INHPTMAFVGLPFNVIPTHIFDMQVRFTLKFFTGQRKFPSREQMIADLEQEIGERWGCGVRNQKK 362
            ...|.|.|:|...:.......::..|:..:...|:...||:|:|   |:|.:           |:
plant   374 PLIPNMGFIGYVQSSSNLKSSELHSRWLSQLLDGKFTLPSKEKM---LDQFL-----------KE 424

  Fly   363 AHQMGERQFVYYNELASIAGIE---------NIKP 388
            .|.|......:.|...|...|:         |:||
plant   425 MHVMRRSSRFFKNHCFSTFSIQHADDLSKDMNLKP 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fmo-2	NP_610217.1	NADB_Rossmann	12..214	CDD:304358	65/246 (26%)
AT5G45180	NP_199331.2	CzcO	9..383	CDD:224983	95/398 (24%)
AT5G45180	NP_199331.2	Pyr_redox_3	14..247	CDD:290456	65/250 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2072
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D405736at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100150
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X69
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.720