Protein Alignment Fmo-2 and FOXRED2

DIOPT Version :9

• Sequence 1: NP_610217.1
• Gene: Fmo-2 / 35561
• FlyBaseID: FBgn0033079
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_001095841.1
• Gene: FOXRED2 / 80020
• HGNCID: 26264
• Length: 684
• Species: Homo sapiens
• Alignment Length: 362
• Identity: 71/362 - (19%)
• Similarity: 119/362 - (32%)
• Gaps: 136/362 - (37%)

  Fly     5 SVDKRR-VCVIGAGTAGLCALKNSLEAGLDAVAYERGTEIGGTWIFSEEMPKD------------ 56
            ||..|| .||:|||.|||........||.|...:||....|.   |....|:.
Human    26 SVPPRRDYCVLGAGPAGLQMAYFLQRAGRDYAVFERAPRPGS---FFTRYPRHRKLISINKRYTG 87

  Fly    57 ----EYDEVHSSMYEGLRTNLPKEVMGYPDYSY-PDDITESFITSNQVLEFLRSYAEHFKLK--- 113
                |::..|.  :..|.::.|:.:..:...:| ||        :..::.:|..:|:...|:
Human    88 KANAEFNLRHD--WNSLLSHDPRLLFRHYSRAYFPD--------ARDMVRYLGDFADTLGLRVQY 142

  Fly   114 ----AHIKLQHEVIRVRPRLDDWEVYVWDHS----TDTCDPVYY-DFVYVCNGHYTEPDLPEVEG 169
                ||:.|            |.:...|:..    ||....|:. ..::|..| .:.|:..:..|
Human   143 NTTIAHVTL------------DKDRQAWNGHYFILTDQKGQVHQCSVLFVATG-LSVPNQVDFPG 194

  Fly   170 LDLFEGNKMHSHLYRKADKFKDARVLIIGAGPSGMD-------ITNHVR-LAAKQVFLSHHLSTT 226
            .:..||   :..:....:.|....|||:|.|.|..:       :||.:. |:..:|.||.
Human   195 SEYAEG---YESVSVDPEDFVGQNVLILGRGNSAFETAENILGVTNFIHMLSRSRVRLSW----- 251

  Fly   227 PNTAFMGNVTQKPDVKRFTKDGAVFT------DGSTES--------------------------- 258
             .|.::|::       |...:|.:.|      ||..||
Human   252 -ATHYVGDL-------RAINNGLLDTYQLKSLDGLLESDLTDLAILKDSKGKFHVTPKFFLEEAN 308

  Fly   259 -----------------------FDHVMFCTGYKYTF 272
                                   :|.|:.|.|:.:.|
Human   309 TNQSADSITLPQDDNDNFAMRVPYDRVIRCLGWNFDF 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fmo-2	NP_610217.1	NADB_Rossmann	12..214	CDD:304358	50/238 (21%)
FOXRED2	NP_001095841.1	CzcO	23..>245	CDD:224983	54/247 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	649..684
		Prevents secretion from ER. /evidence=ECO:0000255|PROSITE-ProRule:PRU10138	681..684

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2072
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810