Protein Alignment Fmo-2 and Fmo9

DIOPT Version :9

• Sequence 1: NP_610217.1
• Gene: Fmo-2 / 35561
• FlyBaseID: FBgn0033079
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_766432.1
• Gene: Fmo9 / 240894
• MGIID: 3606068
• Length: 539
• Species: Mus musculus
• Alignment Length: 476
• Identity: 141/476 - (29%)
• Similarity: 219/476 - (46%)
• Gaps: 131/476 - (27%)

  Fly     8 KRRVCVIGAGTAGLCALKNSLEAGLDAVAYERGTEIGGTWIF----SEEMPKDEYDEVHSSMYEG 68
            |:::.|||||.:||.|:|..|:..|:...:||..:|||.|.|    ||:||         |:|..
Mouse     3 KKQIAVIGAGISGLGAIKCCLDEDLEPTCFERNDDIGGLWKFQKNASEKMP---------SIYRS 58

  Fly    69 LRTNLPKEVMGYPDYSYPDDITESFITSNQVLEFLRSYAEHFKLKAHIKLQHEVIRVRPRLD--- 130
            :..|..||:|.:.|:..||.. .:::.:::::::.|.||:.|.|..:|:.:..|..||.|.|
Mouse    59 VTINTSKEMMCFSDFPIPDHF-PNYMHNSKLMDYFRMYAKRFSLLDYIRFKTTVRSVRKRPDFHI 122

  Fly   131 --DWEVYVWDHSTD-TCDPVYYDFVYVCNGHYTEPDLP--EVEGLDLFEGNKMHSHLYRKADKFK 190
              .|:|.|   .|| ..:.:.:|.|.||:||:|:|.||  ...|::.|||...||..|:..:.:.
Mouse   123 HGQWDVVV---ETDGKQESLVFDGVLVCSGHHTDPHLPLKSFPGIEKFEGCYFHSREYKSPEDYV 184

  Fly   191 DARVLIIGAGPSGMDITNHVRLAAKQVFLS----------------------------------- 220
            ..|::::|.|.||:||...:...|||||||
Mouse   185 GKRIIVVGIGNSGVDIAVELGRVAKQVFLSTRRGSWILHRVWNNGYPMDSSFFTRFHSFLQKILT 249

  Fly   221 -----HHLSTT-----------------------------PNTAFMGNVTQKPDVKRFTKDGAVF 251
                 .:|..|                             ||....|.|..||:||.||.....|
Mouse   250 TEAVNKYLEKTLNSRFNHAHYGLQPQHRPLSQHPTISDDLPNHIISGKVQVKPNVKEFTGTDVHF 314

  Fly   252 TDGST-ESFDHVMFCTGYKYTFPCLSTDVGVQVIDNFVQPLWKHCI--NINHPTMAFVGL--PFN 311
            .||:. |:.|.|:|.|||..:||.|. |: :.|.||.|. |:|...  ::..||:|.:||  |..
Mouse   315 DDGTVEENIDVVIFATGYSISFPFLG-DL-IAVTDNEVS-LYKLMFPPDLEKPTLAVIGLIQPLG 376

  Fly   312 VIPTHIFDMQVRFTLKFFTGQRKFPSREQMIADLEQEIGERWGCGVRNQKKAHQMGERQFV---- 372
            :| ..|.::|.|:.::.|.|..|.||.:.|.||::|            :|||.   |:::|
Mouse   377 II-LPIAELQSRWAVRVFKGLSKLPSVKAMKADMDQ------------RKKAM---EKRYVKTAR 425

  Fly   373 ---------YYNELASIAGIE 384
                     |.:|:||:||::
Mouse   426 HTIQVDHIEYMDEIASLAGVK 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fmo-2	NP_610217.1	NADB_Rossmann	12..214	CDD:304358	71/213 (33%)
Fmo9	NP_766432.1	FMO-like	3..531	CDD:109787	141/476 (30%)
		NAD_binding_8	8..>42	CDD:290186	16/33 (48%)
		NADB_Rossmann	<90..>342	CDD:304358	72/255 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2072
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	206	1.000	Inparanoid score	I3710
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55225
OrthoDB	1	1.010	-	-		D308082at33208
OrthoFinder	1	1.000	-	-		FOG0000093
OrthoInspector	1	1.000	-	-		mtm8771
orthoMCL	1	0.900	-	-		OOG6_100150
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2115
SonicParanoid	1	1.000	-	-		X69
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.810