Protein Alignment Fmo-2 and Fmo6

DIOPT Version :9

• Sequence 1: NP_610217.1
• Gene: Fmo-2 / 35561
• FlyBaseID: FBgn0033079
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_001171509.1
• Gene: Fmo6 / 226565
• MGIID: 2681841
• Length: 532
• Species: Mus musculus
• Alignment Length: 467
• Identity: 129/467 - (27%)
• Similarity: 213/467 - (45%)
• Gaps: 107/467 - (22%)

  Fly     9 RRVCVIGAGTAGLCALKNSLEAGLDAVAYERGTEIGGTWIFSEEMPKDEYDEVHSSMYEGLRTNL 73
            ::|.::|||.:||.|::..||.|||.:.:||..::||.|.||...     :|..:|:|:.:.||.
Mouse     3 KKVAIVGAGVSGLAAIRCCLEEGLDPICFERSIDVGGLWKFSSHA-----EEGRASIYQSVFTNS 62

  Fly    74 PKEVMGYPDYSYPDDITESFITSNQVLEFLRSYAEHFKLKAHIKLQHEVIRVRP-----RLDDWE 133
            .||:|.:||:.||||. .:::..:::.|::.|:|:...|..:|:.:..|..::.     ....|.
Mouse    63 SKEMMCFPDFPYPDDF-PNYMHHSKLQEYITSFAQKKGLLRYIQFETLVSSIKKCSSFLTTGQWV 126

  Fly   134 VYVWDHSTDTCDPVYYDFVYVCNGHYTEPDLP--EVEGLDLFEGNKMHSHLYRKADKFKDARVLI 196
            |........  :.|.:|.|.:|:||:..|::|  ...||:.|.|..:||..|:....|:..:||:
Mouse   127 VVTEKEGKQ--ESVLFDAVMICSGHHVYPNMPTDSFPGLEHFRGKCLHSRDYKGPGAFQGKKVLV 189

  Fly   197 IGAGPSGMDITNHVRLAAKQVFLSHH------------------LSTTPNTAFM----------- 232
            ||.|.|..||...:...|.||.:|..                  :..|..|:|:
Mouse   190 IGLGNSASDIAVELSRLATQVIISTRSGSWIMSRVWNDGYPWDMVYVTRFTSFLRNILPSFVSDW 254

  Fly   233 ----------------------------------------GNVTQKPDVKRFTKDGAVFTDGST- 256
                                                    |.||.||.|.:||:..|||.||:.
Mouse   255 LYIKKMNTWFKHENYGLMPLNGPLRKEPVFNDELPSRILCGMVTIKPIVTKFTETSAVFEDGTVF 319

  Fly   257 ESFDHVMFCTGYKYTFPCLSTDVGVQVIDNFVQPLWKHCI--NINHPTMAFVGLPFNV---IPTH 316
            |:.|.|:|.|||.|.:|.|...: ::..:|.| .|:|...  .:..||||.:||..::   |||
Mouse   320 EAIDCVIFATGYGYAYPFLDDSI-IKSRNNEV-TLYKGIFPPQLEKPTMAVIGLVQSLGAAIPT- 381

  Fly   317 IFDMQVRFTLKFFTGQRKFPSREQMIADLEQEIGE--RW-GCGVRNQKKAHQMGERQFVYYNELA 378
             .|:|.|:..|.||.....|:..:|:.|:::::|:  :| |       ::|.:......|.:||:
Mouse   382 -ADLQARWAAKVFTNTCVLPTTNEMMDDIDEKMGKKLKWFG-------QSHTLQTDYITYMDELS 438

  Fly   379 SIAGIENIKPVI 390
            |..|   .||.|
Mouse   439 SFIG---AKPNI 447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fmo-2	NP_610217.1	NADB_Rossmann	12..214	CDD:304358	64/208 (31%)
Fmo6	NP_001171509.1	FMO-like	2..532	CDD:109787	129/467 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842292
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2072
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	206	1.000	Inparanoid score	I3710
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55225
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000093
OrthoInspector	1	1.000	-	-		mtm8771
orthoMCL	1	0.900	-	-		OOG6_100150
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2115
SonicParanoid	1	1.000	-	-		X69
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.730