Protein Alignment Fmo-2 and fmo-5

DIOPT Version :9

• Sequence 1: NP_610217.1
• Gene: Fmo-2 / 35561
• FlyBaseID: FBgn0033079
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_503352.1
• Gene: fmo-5 / 178596
• WormBaseID: WBGene00001480
• Length: 518
• Species: Caenorhabditis elegans
• Alignment Length: 470
• Identity: 123/470 - (26%)
• Similarity: 204/470 - (43%)
• Gaps: 116/470 - (24%)

  Fly     6 VDKRRVCVIGAGTAGLCALKNS-LEAGLDAVAYERGTEIGGTWIFSEEMPKDEYDEVHSSMYEGL 69
            |.|:::.|:|||.:||.::::: |...::...:|:..:|||.|.|.    .|:.|  .|::.:..
 Worm     2 VAKKQLLVVGAGASGLPSIRHALLHPNVEVTCFEKSGDIGGLWNFK----PDQTD--LSTVMKST 60

  Fly    70 RTNLPKEVMGYPDYSYPDDITESFITSNQVLEFLRSYAEHFKLKAHIKLQHEVIRVRPRLD---- 130
            ..|..||:..|.|:. |:|...:|:.:.::..:|:|||||:.|..||||.|.|:.:....|
 Worm    61 VINTSKEMTAYSDFP-PEDTMANFMHNREMCRYLKSYAEHYGLLKHIKLNHSVVSIERNHDYSTT 124

  Fly   131 -DWEVYVWDHSTDTCDPVYYDFVYVCNGHYTEPDLPEV-EGLDLFEGNKMHSHLYRKADKFKDAR 193
             .|:|...|.|....:.: :|.|.:|:||:..|.:||. .|.:.|:|..:|||.|:....::|..
 Worm   125 GKWKVRYTDESGKFHEKI-FDGVMICSGHHAIPHIPEPWPGQEKFKGRIIHSHDYKDHKGYEDKV 188

  Fly   194 VLIIGAGPSGMDITNHVRLAAKQVFL--------------------------------------- 219
            ::::|.|.||.|....:....|||:|
 Worm   189 IVVVGIGNSGGDCAVELSRIGKQVYLVTRRGSWIFSRLSDRGEPVDLVFNTKFQMQLVDMIPSSI 253

  Fly   220 ---------------------------SHHLSTT---PNTAFMGNVTQKPDVKRFTKDGAVFTDG 254
                                       :.||:..   ||....|.|..||.:|.||:.|..|.||
 Worm   254 MNWNFERILNNKVDHEKYGLKPKHAAMAAHLTLNDELPNRIACGTVRVKPGIKSFTETGVQFDDG 318

  Fly   255 S-TESFDHVMFCTGYKYTFPCLSTDVGVQVIDN------FVQPLWKHCININHPTMAFVGL--PF 310
            | .|..|.|:..||:.|.|..:.....::|.:|      :|.||    ...:|.|:|.:||  |.
 Worm   319 SFVEGVDEVILATGFSYHFDMIEGGKLIEVDENKSDIYKYVFPL----ATADHNTLAVIGLIQPL 379

  Fly   311 -NVIPTHIFDMQVRFTLKFFTGQRKFPSREQMIADLEQEIGERWGCGVRNQKKAHQMGERQFV-- 372
             :::|  |.:||.|..::.|....|.||::||:.|:.::         |....|..:..|:..
 Worm   380 GSIMP--ISEMQARVYMESFANGMKLPSKDQMLTDIAEK---------REIMSARYVASRRHTIQ 433

  Fly   373 -----YYNELASIAG 382
                 |.:||..|.|
 Worm   434 VDYASYMHELGEIIG 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fmo-2	NP_610217.1	NADB_Rossmann	12..214	CDD:304358	63/208 (30%)
fmo-5	NP_503352.1	FMO-like	4..511	CDD:109787	122/468 (26%)
		NADB_Rossmann	8..222	CDD:304358	67/221 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162413
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2072
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55225
OrthoDB	1	1.010	-	-		D308082at33208
OrthoFinder	1	1.000	-	-		FOG0000093
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100150
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2115
SonicParanoid	1	1.000	-	-		X69
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.690