DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Trap1 and SHD

DIOPT Version :9

Sequence 1:	NP_001260726.1	Gene:	Trap1 / 35559	FlyBaseID:	FBgn0026761	Length:	691	Species:	Drosophila melanogaster
Sequence 2:	NP_194150.1	Gene:	SHD / 828520	AraportID:	AT4G24190	Length:	823	Species:	Arabidopsis thaliana

Alignment Length:	764	Identity:	237/764 - (31%)
Similarity:	388/764 - (50%)	Gaps:	143/764 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 RQSHRSA---------PAAFNITIGSQHSPGALSL------RRYSTETKQASGSVVDKHEFQAET 72
            |:.|.:|         |......||..   |.||.      |...:.:|:...|..:|.|||||.
plant    24 RKLHANAEESSDDVTDPPKVEEKIGGH---GGLSTDSDVVHRESESMSKKTLRSNAEKFEFQAEV 85

  Fly    73 RQLLDIVARSLYSDHEVFVRELISNASDALEKFRYTSLSAGGENLAGKDRPLEIRITTDKPLMQL 137
            .:|:||:..||||:.::|:|||||||||||:|.|:.:|:.......|....|||:|..||....|
plant    86 SRLMDIIINSLYSNKDIFLRELISNASDALDKIRFLALTDKDVLGEGDTAKLEIQIKLDKAKKIL 150

  Fly   138 IIQDTGIGMTKEELVSNLGTIARSGSKKFLEQMKGTQQGASSEASSNIIGQFGVGFYSSFIVANK 202
            .|:|.|||||||:|:.||||||:||:..|:|:|:       |....|:||||||||||:::||:.
plant   151 SIRDRGIGMTKEDLIKNLGTIAKSGTSAFVEKMQ-------SSGDLNLIGQFGVGFYSAYLVADY 208

  Fly   203 VEVFTRAAVPNAPGLRWSTDGSGTYEIEE---VPDVELGTRIVLHLKTDCREYADEERIKAVIKK 264
            :||.::.  .:.....|.:..:|.:.:.|   ...:..||.|.|||:.:..||.:|.::|.::|:
plant   209 IEVISKH--NDDSQYVWESKANGKFAVSEDTWNEPLGRGTEIRLHLRDEAGEYLEESKLKELVKR 271

  Fly   265 YSNFVGSPILL--------------------------------------NGKQ------------ 279
            ||.|:..||.|                                      :|::
plant   272 YSEFINFPISLWASKEVETEVPVEEDESADEETETTSTEEEKEEDAEEEDGEKKQKTKKVKETVY 336

  Fly   280 ----ANEIKPLWLLEPQSISKEQHHDFYRFISNSF--DVPRFTLHYNADVPLSIHALLYFPEGKP 338
                .|::|.:||..|:.:::|::..||..:|..|  :.|....|:||:..:...|:||.|...|
plant   337 EWELLNDVKAIWLRSPKEVTEEEYTKFYHSLSKDFTDEKPMAWSHFNAEGDVEFKAVLYVPPKAP 401

  Fly   339 -GLFEMSRDGN-TGVALYTRKVLIQSKTEHLLPKWLRFVKGVVDSEDIPLNLSRELLQNSSLIRK 401
             .|:|...:.| ..:.||.|:|.|..:.:.||||:|.|:||:|||:.:|||:|||:||..|.::.
plant   402 HDLYESYYNSNKANLKLYVRRVFISDEFDELLPKYLSFLKGLVDSDTLPLNVSREMLQQHSSLKT 466

  Fly   402 LSSVISTRVIRFLQERSKKQPEE---------------------YEAFYRDYGLFLKEGIVTSSD 445
            :...:..:.:..:::.:::.|:|                     |..|:.::|..:|.||:  .|
plant   467 IKKKLIRKALDMIRKLAEEDPDEIHDDEKKDVEKSGENDEKKGQYTKFWNEFGKSVKLGII--ED 529

  Fly   446 ASEKEEIAKLLRFESSKSETASGRM-SLEEYYNAVPAEQQNIYYLAAPNRVLAESSPYYESLKKR 509
            |:.:..:|||||||::||:   |:: ||::|...:...|::|:|:...::...|.||:.|.|.|:
plant   530 AANRNRLAKLLRFETTKSD---GKLTSLDQYIKRMKKSQKDIFYITGSSKEQLEKSPFLERLIKK 591

  Fly   510 NELVLFCYEPYDELVLMQLGKFKSKKLVSVEKE---MREESKETTATTDFGEGSLLRSELDTLIP 571
            ...|:|..:|.||.::..|..::.||..:|.||   :.::||:......|.|          |..
plant   592 GYEVIFFTDPVDEYLMQYLMDYEDKKFQNVSKEGLKVGKDSKDKELKEAFKE----------LTK 646

  Fly   572 WLEEELRGQ-VIKVKATTRLDTHPCVITVEEMAAARHFIR-TQSHQVPEQNRFALLQPE--LEIN 632
            |.:..|..: |..||.:.||...|||:...:...:.:..| .||..:.:.|:.|.::.:  ||||
plant   647 WWKGNLASENVDDVKISNRLADTPCVVVTSKFGWSANMERIMQSQTLSDANKQAYMRGKRVLEIN 711

  Fly   633 PKHPIIKKLNKLRESD------KDLAQLIAKQLFANAMVGAG-LAEDPR 674
            |:|||||:|.....||      |:.|||    ::..|::.:| :..||:
plant   712 PRHPIIKELKDRIASDPEDESVKETAQL----MYQTALIESGFILTDPK 756

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Trap1	NP_001260726.1	PRK05218	65..689	CDD:235366	225/707 (32%)
		HATPase_c	91..246	CDD:280651	67/157 (43%)
		HSP90	251..688	CDD:278607	143/518 (28%)
SHD	NP_194150.1	PRK05218	74..763	CDD:235366	226/711 (32%)
		HATPase_c	104..253	CDD:280651	67/157 (43%)
		HSP90	258..775	CDD:278607	143/518 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0326
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D924636at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820