Protein Alignment Trap1 and hsp90aa1.2

DIOPT Version :9

• Sequence 1: NP_001260726.1
• Gene: Trap1 / 35559
• FlyBaseID: FBgn0026761
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: NP_001038538.1
• Gene: hsp90aa1.2 / 565155
• ZFINID: ZDB-GENE-031001-3
• Length: 734
• Species: Danio rerio
• Alignment Length: 715
• Identity: 227/715 - (31%)
• Similarity: 363/715 - (50%)
• Gaps: 115/715 - (16%)

  Fly    54 ETKQASGSVVDKHEFQAETRQLLDIVARSLYSDHEVFVRELISNASDALEKFRYTSLSAGGENLA 118
            |.:......|:...||||..||:.::..:.||:.|:|:||||||:||||:|.||.||:...:..:
Zfish     6 EQQMMEDEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDS 70

  Fly   119 GKDRPLEIRITTDKPLMQLIIQDTGIGMTKEELVSNLGTIARSGSKKFLEQMKGTQQGASSEASS 183
            |||  |:|.|..:|....|.|.||||||||.:|::||||||:||:|.|:|.:   |.|    |..
Zfish    71 GKD--LKIEIIPNKEERTLTIIDTGIGMTKADLINNLGTIAKSGTKAFMEAL---QAG----ADI 126

  Fly   184 NIIGQFGVGFYSSFIVANKVEVFTRAAVPNAPGLRWSTDGSGTYEIEEVPDVELGTRIVLHLKTD 248
            ::||||||||||:::||.||.|.|:...........|..||.|.:::....:..||:::||||.|
Zfish   127 SMIGQFGVGFYSAYLVAEKVTVITKHLDDEQYAWESSAGGSFTVKVDNSEPIGRGTKVILHLKED 191

  Fly   249 CREYADEERIKAVIKKYSNFVGSPILL-------------------------------------- 275
            ..||.:|.|||.::||:|.|:|.||.|
Zfish   192 QTEYIEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEEKEKEKEEEEEGEKDEDKPEI 256

  Fly   276 -------------------------------NGKQANEIKPLWLLEPQSISKEQHHDFYRFISNS 309
                                           :.::.|:.||||...|..|:.|::.:||:.::|.
Zfish   257 EDVGSDEDDHDHGDKCGDKKKKKKKIKEKYIDQEELNKTKPLWTRNPDDITNEEYGEFYKSLTND 321

  Fly   310 FDVPRFTLHYNADVPLSIHALLYFPEGKP-GLFEMSRDGNTGVALYTRKVLIQSKTEHLLPKWLR 373
            ::......|::.:..|...|||:.|...| .|||..:..| .:.||.|:|.|....:.|:|::|.
Zfish   322 WEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENKKKKN-NIKLYVRRVFIMDNCDELIPEYLN 385

  Fly   374 FVKGVVDSEDIPLNLSRELLQNSSLIRKLSSVISTRVIRFLQERSKKQPEEYEAFYRDYGLFLKE 438
            |:||||||||:|||:|||:||.|.:::.:...:..:.:....|.::.: :.|:.:|..:...:|.
Zfish   386 FIKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDK-DNYKKYYEQFSKNIKL 449

  Fly   439 GIVTSSDASEKEEIAKLLRFESSKSETASG--RMSLEEYYNAVPAEQQNIYYLAAPNRVLAESSP 501
            ||  ..|:..::::::|||:.:|    |||  .:||::|...:...|::|||:....:....:|.
Zfish   450 GI--HEDSQNRKKLSELLRYYTS----ASGDEMVSLKDYVTRMKDTQKHIYYITGETKDQVANSA 508

  Fly   502 YYESLKKRNELVLFCYEPYDELVLMQLGKFKSKKLVSVEK---EMREESKETTATTDFGEGSLLR 563
            :.|.|:|....|::..||.||..:.||.:|:.|.||||.|   |:.|:.:|.....:      .:
Zfish   509 FVERLRKAGLEVIYMIEPIDEYCVQQLKEFEGKNLVSVTKEGLELPEDEEEKKKQEE------KK 567

  Fly   564 SELDTLIPWLEEELRGQVIKVKATTRLDTHPCVITVEEMAAARHFIRTQSHQVPEQNR---FALL 625
            |:.:.|...:::.|..:|.||..:.||.:.||.|.........:..|....|....|.   :...
Zfish   568 SKFENLCKIMKDILEKKVEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAA 632

  Fly   626 QPELEINPKHPIIKKLNKLRESD------KDLAQLIAKQLFANAMVGAGLA-EDPRMLLTNMNTL 683
            :..|||||.|||::.|.:..|:|      |||..|    ||..|::.:|.. :||:   |:.|.:
Zfish   633 KKHLEINPDHPIVETLRQKAEADKNDKSVKDLVIL----LFETALLSSGFTLDDPQ---THSNRI 690

  Fly   684  683
            Zfish   691  690

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trap1	NP_001260726.1	PRK05218	65..689	CDD:235366	225/704 (32%)
		HATPase_c	91..246	CDD:280651	71/154 (46%)
		HSP90	251..688	CDD:278607	141/518 (27%)
hsp90aa1.2	NP_001038538.1	PTZ00272	16..734	CDD:240341	225/705 (32%)
		HATPase_c	38..189	CDD:214643	73/159 (46%)
		HSP90	194..724	CDD:278607	141/518 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0326
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D924636at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820