| Sequence 1: | NP_001260726.1 | Gene: | Trap1 / 35559 | FlyBaseID: | FBgn0026761 | Length: | 691 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001258898.1 | Gene: | HSP90AB1 / 3326 | HGNCID: | 5258 | Length: | 724 | Species: | Homo sapiens |
| Alignment Length: | 694 | Identity: | 228/694 - (32%) |
|---|---|---|---|
| Similarity: | 358/694 - (51%) | Gaps: | 98/694 - (14%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 63 VDKHEFQAETRQLLDIVARSLYSDHEVFVRELISNASDALEKFRYTSLSAGGENLAGKDRPLEIR 127
Fly 128 ITTDKPLMQLIIQDTGIGMTKEELVSNLGTIARSGSKKFLEQMKGTQQGASSEASSNIIGQFGVG 192
Fly 193 FYSSFIVANKVEVFTRAAVPNAPGLRWSTDGSGTYEIEEVPDVELGTRIVLHLKTDCREYADEER 257
Fly 258 IKAVIKKYSNFVGSPILL---------------------------------------------NG 277
Fly 278 K-----------------QANEIKPLWLLEPQSISKEQHHDFYRFISNSFDVPRFTLHYNADVPL 325
Fly 326 SIHALLYFPEGKP-GLFEMSRDGNTGVALYTRKVLIQSKTEHLLPKWLRFVKGVVDSEDIPLNLS 389
Fly 390 RELLQNSSLIRKLSSVISTRVIRFLQERSKKQPEEYEAFYRDYGLFLKEGIVTSSDASEKEEIAK 454
Fly 455 LLRFESSKSETASGRMSLEEYYNAVPAEQQNIYYLAAPNRVLAESSPYYESLKKRNELVLFCYEP 519
Fly 520 YDELVLMQLGKFKSKKLVSVEKEMREESKETTATTDFGEGSLLRSELDTLIPWLEEELRGQVIKV 584
Fly 585 KATTRLDTHPCVITVEEMAAARHFIRTQSHQVPEQNR---FALLQPELEINPKHPIIKKLNKLRE 646
Fly 647 SD------KDLAQLIAKQLFANAMVGAGLA-EDPRMLLTNMNTL 683 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Trap1 | NP_001260726.1 | PRK05218 | 65..689 | CDD:235366 | 227/692 (33%) |
| HATPase_c | 91..246 | CDD:280651 | 69/154 (45%) | ||
| HSP90 | 251..688 | CDD:278607 | 145/506 (29%) | ||
| HSP90AB1 | NP_001258898.1 | Interaction with TP53. /evidence=ECO:0000269|PubMed:15358771 | 2..527 | 180/529 (34%) | |
| Interaction with BIRC2. /evidence=ECO:0000269|PubMed:25486457 | 2..214 | 95/210 (45%) | |||
| Interaction with NR3C1. /evidence=ECO:0000250|UniProtKB:P11499 | 9..231 | 97/227 (43%) | |||
| PTZ00272 | 14..724 | CDD:240341 | 227/692 (33%) | ||
| Interaction with AHSA1. /evidence=ECO:0000269|PubMed:25486457 | 215..552 | 93/342 (27%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 222..270 | 2/47 (4%) | |||
| Interaction with NR3C1. /evidence=ECO:0000250|UniProtKB:P11499 | 264..608 | 103/352 (29%) | |||
| Interaction with NR1D1. /evidence=ECO:0000250|UniProtKB:P11499 | 620..723 | 24/68 (35%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 696..724 | ||||
| TPR repeat-binding | 720..724 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG0326 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D924636at2759 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.820 | |||||