Protein Alignment Trap1 and hsp90

DIOPT Version :10

• Sequence 1: NP_477439.2
• Gene: Trap1 / 35559
• FlyBaseID: FBgn0026761
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: NP_594365.1
• Gene: hsp90 / 2543539
• PomBaseID: SPAC926.04C
• Length: 704
• Species: Schizosaccharomyces pombe
• Alignment Length: 698
• Identity: 231/698 - (33%)
• Similarity: 362/698 - (51%)
• Gaps: 97/698 - (13%)

  Fly    61 SVVDKHEFQAETRQLLDIVARSLYSDHEVFVRELISNASDALEKFRYTSLSAGGENLAGKDRPLE 125
            |..:..:|:||..||:.::..::||:.|:|:|||||||||||:|.||.|||......|.||  |.
pombe     2 SNTETFKFEAEISQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQSLSDPHALDAEKD--LF 64

  Fly   126 IRITTDKPLMQLIIQDTGIGMTKEELVSNLGTIARSGSKKFLEQMKGTQQGASSEASSNIIGQFG 190
            ||||.||....|.|:||||||||.:|::|||.||:||:|:|:|       .|:|.|..::|||||
pombe    65 IRITPDKENKILSIRDTGIGMTKNDLINNLGVIAKSGTKQFME-------AAASGADISMIGQFG 122

  Fly   191 VGFYSSFIVANKVEVFTRAAVPNAPGLRWSTDGSGTYEI---EEVPDVELGTRIVLHLKTDCREY 252
            |||||:::||:||:|.::.  .:.....|.:...|::.:   .:.|.:..||.|.|.:|.|..:|
pombe   123 VGFYSAYLVADKVQVVSKH--NDDEQYIWESSAGGSFTVTLDTDGPRLLRGTEIRLFMKEDQLQY 185

  Fly   253 ADEERIKAVIKKYSNFVGSPILL------------------------------------------ 275
            .:|:.||..:||:|.|:..||.|
pombe   186 LEEKTIKDTVKKHSEFISYPIQLVVTREVEKEVPEEEETEEVKNEEDDKAPKIEEVDDESEKKEK 250

  Fly   276 ----------NGKQANEIKPLWLLEPQSISKEQHHDFYRFISNSFDVPRFTLHYNADVPLSIHAL 330
                      ..::.|:.||:|...|..::||::..||:.::|.::......|::.:..|...|:
pombe   251 KTKKVKETTTETEELNKTKPIWTRNPSEVTKEEYASFYKSLTNDWEDHLAVKHFSVEGQLEFRAI 315

  Fly   331 LYFPEGKP-GLFEMSRDGNTGVALYTRKVLIQSKTEHLLPKWLRFVKGVVDSEDIPLNLSRELLQ 394
            |:.|...| .|||..|..| .:.||.|:|.|....|.|:|:||.|:||||||||:|||||||:||
pombe   316 LFVPRRAPMDLFEAKRKKN-NIKLYVRRVFITDDCEELIPEWLGFIKGVVDSEDLPLNLSREMLQ 379

  Fly   395 NSSLIRKLSSVISTRVIRFLQERSKKQPEEYEAFYRDYGLFLKEGIVTSSDASEKEEIAKLLRFE 459
            .:.:::.:...:..|.:....|.::.: |.::.||..:...||.||  ..||:.:..:|||||:.
pombe   380 QNKIMKVIRKNLVRRCLDMFNEIAEDK-ENFKTFYDAFSKNLKLGI--HEDAANRPALAKLLRYN 441

  Fly   460 SSKSETASGRMSLEEYYNAVPAEQQNIYYLAAPNRVLAESSPYYESLKKRNELVLFCYEPYDELV 524
            |..|  ....:|||:|...:|..|:|||::...::...|:||:.|..:.:...|||..:|.||..
pombe   442 SLNS--PDDLISLEDYITKMPEHQKNIYFITGESKQAVENSPFLEIFRAKKFDVLFMVDPIDEYA 504

  Fly   525 LMQLGKFKSKKLVSVEK---EMREESKETTATTDFGEGSLLRSELDTLIPWLEEELRGQVIKVKA 586
            :.||.:|:.||||::.|   |:.|..:|..|.      ..|..|.:.....|:..|..:|.||..
pombe   505 VTQLKEFEGKKLVNITKDGLELEETDEEKAAR------EKLEKEYEEFAKQLKTILGDKVEKVVV 563

  Fly   587 TTRLDTHPCVITVEE---MAAARHFIRTQSHQVPEQNRFALLQPELEINPKHPIIKKLNKLRE-- 646
            :.::...||::|..:   .|.....::.|:.:....:.:...:...|||||.|||.:|.|..|
pombe   564 SNKIVGSPCLLTTGQYGWSANMERIMKAQALRDTSMSAYMSSRKTFEINPKSPIIAELKKKVEEN 628

  Fly   647 -----SDKDLAQLIAKQLFANAMVGAGLA-EDPRMLLTNMNTLLSRAL 688
                 |.||||.:    |:..|::.:|.. :||......:|.|:|..|
pombe   629 GAEDRSVKDLATI----LYETALLSSGFTLDDPSAYAQRINRLISLGL 672

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trap1	NP_477439.2	HtpG	65..689	CDD:440095	230/694 (33%)
hsp90	NP_594365.1	HSP90	4..704	CDD:481033	230/696 (33%)