Protein Alignment Trap1 and hsp-90

DIOPT Version :10

• Sequence 1: NP_477439.2
• Gene: Trap1 / 35559
• FlyBaseID: FBgn0026761
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: NP_506626.1
• Gene: hsp-90 / 179971
• WormBaseID: WBGene00000915
• Length: 702
• Species: Caenorhabditis elegans
• Alignment Length: 680
• Identity: 221/680 - (32%)
• Similarity: 366/680 - (53%)
• Gaps: 80/680 - (11%)

  Fly    68 FQAETRQLLDIVARSLYSDHEVFVRELISNASDALEKFRYTSLSAGGENLAGKDRPLEIRITTDK 132
            ||||..||:.::..:.||:.|:::|||||||||||:|.||.:|:...|...||:  |.|:||.:|
 Worm    10 FQAEIAQLMSLIINTFYSNKEIYLRELISNASDALDKIRYQALTEPSELDTGKE--LFIKITPNK 72

  Fly   133 PLMQLIIQDTGIGMTKEELVSNLGTIARSGSKKFLEQMKGTQQGASSEASSNIIGQFGVGFYSSF 197
            ....|.|.||||||||.:||:||||||:||:|.|:|.:   |.|    |..::||||||||||:|
 Worm    73 EEKTLTIMDTGIGMTKADLVNNLGTIAKSGTKAFMEAL---QAG----ADISMIGQFGVGFYSAF 130

  Fly   198 IVANKVEVFTRAAVPNAPGLRWSTDGSGTYEIEEV--PDVELGTRIVLHLKTDCREYADEERIKA 260
            :||:||.|.::.  .:....:|.:...|::.:...  |:|..||:||:|:|.|..::.:|.:||.
 Worm   131 LVADKVVVTSKN--NDDDSYQWESSAGGSFVVRPFNDPEVTRGTKIVMHIKEDQIDFLEERKIKE 193

  Fly   261 VIKKYSNFVGSPILL------------------------------------------------NG 277
            ::||:|.|:|.||.|                                                ..
 Worm   194 IVKKHSQFIGYPIKLVVEKEREKEVEDEEAVEAKDEEKKEGEVENVADDADKKKTKKIKEKYFED 258

  Fly   278 KQANEIKPLWLLEPQSISKEQHHDFYRFISNSFDVPRFTLHYNADVPLSIHALLYFPEGKP-GLF 341
            ::.|:.||:|...|..||.|::.:||:.:||.::......|::.:..|...|||:.|:..| .||
 Worm   259 EELNKTKPIWTRNPDDISNEEYAEFYKSLSNDWEDHLAVKHFSVEGQLEFRALLFVPQRAPFDLF 323

  Fly   342 EMSRDGNTGVALYTRKVLIQSKTEHLLPKWLRFVKGVVDSEDIPLNLSRELLQNSSLIRKLSSVI 406
            |..:..|: :.||.|:|.|....|.|:|::|.|:||||||||:|||:|||:||.|.:::.:...:
 Worm   324 ENKKSKNS-IKLYVRRVFIMENCEELMPEYLNFIKGVVDSEDLPLNISREMLQQSKILKVIRKNL 387

  Fly   407 STRVIRFLQERSKKQPEEYEAFYRDYGLFLKEGIVTSSDASEKEEIAKLLRFESSKSETASGRMS 471
            ..:.:..:.|.::.: :.::.||..:|..||.||  ..|::.:::::..||:.:|..:..:   |
 Worm   388 VKKCMELIDEVAEDK-DNFKKFYEQFGKNLKLGI--HEDSTNRKKLSDFLRYSTSAGDEPT---S 446

  Fly   472 LEEYYNAVPAEQQNIYYLAAPNRVLAESSPYYESLKKRNELVLFCYEPYDELVLMQLGKFKSKKL 536
            |:||.:.:...|..|||:...::.:..:|.:.|.:|.|...||:..:|.||..:.||.::..|||
 Worm   447 LKEYVSRMKENQTQIYYITGESKDVVAASAFVERVKSRGFEVLYMCDPIDEYCVQQLKEYDGKKL 511

  Fly   537 VSVEKEMREESKETTATTDFGEGSLLRSELDTLIPWLEEELRGQVIKVKATTRLDTHPCVITVEE 601
            |||.||..|..:.......|.|..:....|..:|   ::.|..:|.||..:.||.:.||.|...|
 Worm   512 VSVTKEGLELPETEEEKKKFEEDKVAYENLCKVI---KDILEKKVEKVGVSNRLVSSPCCIVTSE 573

  Fly   602 ---MAAARHFIRTQSHQVPEQNRFALLQPELEINPKHPIIKKLN---KLRESDKDLAQLIAKQLF 660
               .|.....::.|:.:......:...:..|||||.|.|:|.|.   ::.::||.:..|:. .||
 Worm   574 YGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHAIMKTLRDRVEVDKNDKTVKDLVV-LLF 637

  Fly   661 ANAMVGAGLA-EDPRMLLTNMNTLLSRALE 689
            ..|::.:|.: |:|:...:.:..::...|:
 Worm   638 ETALLASGFSLEEPQSHASRIYRMIKLGLD 667

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trap1	NP_477439.2	HtpG	65..689	CDD:440095	220/678 (32%)
hsp-90	NP_506626.1	HSP90	6..702	CDD:481033	221/680 (33%)