DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pld and Pld6

DIOPT Version :9

Sequence 1:	NP_001137610.1	Gene:	Pld / 35554	FlyBaseID:	FBgn0286511	Length:	1364	Species:	Drosophila melanogaster
Sequence 2:	NP_001277212.1	Gene:	Pld6 / 194908	MGIID:	2687283	Length:	221	Species:	Mus musculus

Alignment Length:	109	Identity:	29/109 - (26%)
Similarity:	50/109 - (45%)	Gaps:	29/109 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly  1121 GIAVRAITHWNYASISRGRTSILTRLQEAGIANPENYISFHSLRNHSFLNNTPITELIYVHSKLL 1185
            |:.||.||..:|.:::..:..:   |::|||          .:|:..        :|.|:|.|..
Mouse   114 GVRVRVITDCDYMALNGSQIGL---LRKAGI----------QVRHDQ--------DLGYMHHKFA 157

  Fly  1186 IADDRVVICGSANINDRSMIGKR-------DSEIAAILMDEEFE 1222
            |.|.:|:|.||.|...:::...|       |:|...:.: ||||
Mouse   158 IVDKKVLITGSLNWTTQAIQNNRENVLIMEDTEYVRLFL-EEFE 200

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pld	NP_001137610.1	PX_PLD	230..431	CDD:132805
		PH_PLD	419..564	CDD:269956
		PLDc_vPLD1_2_yPLD_like_1	590..734	CDD:197236
		PLDc_vPLD1_2_yPLD_like_2	1032..1220	CDD:197239	25/105 (24%)
Pld6	NP_001277212.1	Required for mitochondrial localization	1..38
		PLDc_vPLD6_like	92..203	CDD:197268	29/109 (27%)
		PLDc_2	93..203	CDD:289836	29/109 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1502
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900