DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment tomboy40 and tom40

DIOPT Version :9

Sequence 1:	NP_610213.1	Gene:	tomboy40 / 35553	FlyBaseID:	FBgn0033074	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_595546.2	Gene:	tom40 / 2540506	PomBaseID:	SPBC27B12.13	Length:	344	Species:	Schizosaccharomyces pombe

Alignment Length:	331	Identity:	85/331 - (25%)
Similarity:	143/331 - (43%)	Gaps:	50/331 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 QMVEALKAEAKKPELTNPGTLEELHSR-CRDIQAN--TFEGAKIMVNKGL--SNHFQVTHTINMN 98
            |:.|.:.:......|.||||.|.|... .:||..:  .|.|.:..|.||.  |..|.|:|...:.
pombe    13 QVGEKIDSYKSSLNLINPGTCENLSKEVSKDILLSNYAFTGVRADVTKGFCTSPWFTVSHAFALG 77

  Fly    99 SAGPSGYRFGATYVGTKQYGPTEAFPVLLGEIDPMGNLNANVIHQLTSRLRCKFASQFQDSKLVG 163
            |.....|.|...:.|...:        |.|.:|..|.:.|.:.....|.:..|...|..:..:..
pombe    78 SQVLPPYSFSTMFGGEPLF--------LRGSVDNDGAVQAMLNCTWNSNVLSKVQMQLSNGAVPN 134

  Fly   164 -TQLTGDYRGRDYTLTLTMGNPGFFTS-SGVFVCQYLQSVTKRLALGSEFAYHYGPNVPGRQVAV 226
             .|:..|::|:|::.:....||.:... :|:::...|||||.:|:||.|..:....:..|.:.|.
pombe   135 MCQIEHDHKGKDFSFSFKAMNPWYEEKLTGIYIISLLQSVTPKLSLGVEALWQKPSSSIGPEEAT 199

  Fly   227 LSAVGRYAFGDTVWSCTLGPAGFHL---------SYYQKASDQLQIGVEVE-------------T 269
            ||.:.||...|  |..|.     ||         ::::|.|.:::.|||.:             |
pombe   200 LSYMTRYNAAD--WIATA-----HLNGSQGDVTATFWRKLSPKVEAGVECQLSPVGLNHSAALMT 257

  Fly   270 NIRQQESTAT-VAYQIDLPKADLVFRGSLDSNWLISGVLEKRLQPLPFSLAISGRMNHQKNSFRL 333
            ..:.:..|:. |.|:.    |..::||.:||...:...||:||.| ..:||.|..::|...:.::
pombe   258 GPKPEGLTSVGVKYEF----AQSIYRGQVDSKGRVGVYLERRLAP-AITLAFSSELDHPNRNAKV 317

  Fly   334 GCGLMI 339
            |.||.:
pombe   318 GLGLSL 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tomboy40	NP_610213.1	Porin3_Tom40	53..340	CDD:132766	83/317 (26%)
tom40	NP_595546.2	Porin3_Tom40	27..324	CDD:132766	83/317 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	94	1.000	Domainoid score	I1958
eggNOG	1	0.900	-	-		E1_KOG3296
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H101105
Inparanoid	1	1.050	100	1.000	Inparanoid score	I1660
OMA	1	1.010	-	-		QHG55758
OrthoFinder	1	1.000	-	-		FOG0001620
OrthoInspector	1	1.000	-	-		otm47115
orthoMCL	1	0.900	-	-		OOG6_101593
Panther	1	1.100	-	-	O	PTHR10802
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.830