Protein Alignment bin3 and Mepce

DIOPT Version :10

• Sequence 1: NP_523626.2
• Gene: bin3 / 35552
• FlyBaseID: FBgn0263144
• Length: 1367
• Species: Drosophila melanogaster
• Sequence 2: NP_001094148.1
• Gene: Mepce / 304361
• RGDID: 1560550
• Length: 660
• Species: Rattus norvegicus
• Alignment Length: 981
• Identity: 236/981 - (24%)
• Similarity: 353/981 - (35%)
• Gaps: 366/981 - (37%)

  Fly   160 GGGGG--AGAHHAAAGGHHHHHNTR----LAQNAAAGGASGGG-TIQMHKKMLRGHHHHVLCAGN 217
            |||||  ..:|..||.|.......|    .|.:|.|..:.||| ..|.|     |..|....|..
  Rat    25 GGGGGPEVRSHQEAASGELLDGTERGPGPRAHSAGATASGGGGPQAQTH-----GEPHGRAAAPA 84

  Fly   218 NANHTCCLVTGCNGSSIGGVGVA----GSGGATASAGGGGASCKEAQSCKDTSSLSGNSSIAGSA 278
            :....   ..|..|:.:|.....    |........||||   |...||          ::.|.:
  Rat    85 DVGEE---RRGGGGTDLGPPAPPRPRNGYQPHRPPVGGGG---KRRNSC----------NVGGGS 133

  Fly   279 GAGNAVHYCCGRSKFFLPEKRLRKEV-----IVPPTKFLLGGNISDPLNLNSLQNENTSNASSTN 338
            | |:..|          |..:.|:.|     .|.|:.|||||||.||||||||.:|..|.|.:
  Rat   134 G-GSFKH----------PAFKRRRRVNSDCDSVLPSNFLLGGNIFDPLNLNSLLDEEVSRALN-- 185

  Fly   339 NTPATTPRQSPITTPPK----VEVIIPPNIHDPLHLLDPVDSMEYEKQLTSPMKRAGPGGGMLHH 399
               |.||:.||:  |.|    ||::||.:|.|||.|....|  |....|.||:|        :..
  Rat   186 ---AETPKSSPL--PAKGRDPVEILIPKDITDPLSLNTCTD--EAHVVLASPLK--------IGR 235

  Fly   400 RQHHYRTRKNRKRRRFDSNNTSHAGDEGGVGSELTDEPPLPAATSSLAASPVAAPLNVGGSLLLS 464
            ::|.:|...:::::....|::.         :.|..:|..|               :|.|.
  Rat   236 KRHRHRGPHHQQQQASGGNDSQ---------AVLPTDPLTP---------------SVHGE---- 272

  Fly   465 ESAAPAPGETAE-MGQQQEQAHVHSPQSASTTTTAAEMPTPTPTSAAAATATAEHKEQSAPAPTA 528
                   |.|.: .||.::....:...:|.........|.|:....::.:.:|........||::
  Rat   273 -------GATQQHRGQNRDDPQPYELNTAINCRDEVVSPLPSALQGSSGSLSAPPAASVTSAPSS 330

  Fly   529 TSSPQRQQQHVAAAAEELPTPETSAAAETPAEEMLLSCSATSASLVASTLAERRASRDLRLDLSS 593
            :||..|:::            .||:.:|..|.
  Rat   331 SSSRHRKRR------------RTSSKSEAGAR--------------------------------- 350

  Fly   594 TCYGVGGTGLSFGGSISSSVGSSFGGGGRKRKISESSTSQKSKKFHRHDAMDKIVSPVVPQPGAW 658
                        |||..|.......||||                |.|
  Rat   351 ------------GGSQGSKEKGRGSGGGR----------------HHH----------------- 370

  Fly   659 KRPPRILQPSGARKPSTRRSTSVSESELLSPVEEQPPKQLPLIGVEIPRDDTPDLPDHGLGSPLS 723
                                                                          ||.
  Rat   371 --------------------------------------------------------------PLP 373

  Fly   724 TTSGATSHTAGEQDSLAGVDISMGDTLGSGVVGKAPLTSSLMLEPAKIPPIKMLPKFRADGLKYR 788
            .|.                                                     |:...||::
  Rat   374 ATG-----------------------------------------------------FKKQQLKFQ 385

  Fly   789 YGNFDRYVDFRQMNEFRDVRLQVFQRHVELFENKDILDIGCNVGHMTITVARHLAPKTIVGIDID 853
            |||:.:|..:|..: ..|:||:|.:  .|.|:.:|:||:||||||:|:::|....|..:||:|||
  Rat   386 YGNYCKYYGYRNPS-CEDMRLRVLK--PEWFQGRDVLDLGCNVGHLTLSIACKWGPARMVGLDID 447

  Fly   854 RELVARARRNLSIFVRIPKEEKLLEVKAEPTVDAKANIAVKDETSGAAHKKTRRGKRRRKVHQGI 918
            ..|:..||:|:..::   .||..|:.                        :|..|....:..:|
  Rat   448 PRLIHSARQNIRHYL---SEELRLQA------------------------QTSEGDPGTEGEEG- 484

  Fly   919 HHHHHHHHDLEQLQQQQKLNSLLVKPHEFFPISFPLTYGRIPRILSSSKSPNMLGNKNQFPANVF 983
                                :..|:....||.|  ||..|.|  :::...|....:.:.||.||.
  Rat   485 --------------------TTTVRKRSCFPAS--LTASRGP--IAAPHLPLDGADTSVFPNNVV 525

  Fly   984 FRHTNYVLKDESLMASDTQQYDLILCLSVTKWIHLNFGDNGLKMAFKRMFNQLRPGGKLILEAQN 1048
            |...||||..:.|:.:...:||::||.|:|||:|||:||.|||..|:|::..|||||.|:||.|.
  Rat   526 FVTGNYVLDRDELVDAQRPEYDVVLCFSLTKWVHLNWGDEGLKRMFRRIYRHLRPGGILVLEPQP 590

  Fly  1049 WASYKKKKNLTPEIYNNYKQIEFFPNKFHEYLLSSEVGFSHSYTLGVPRHMNKGFCRPIQLYAKG 1113
            |:||.::|:||..||.||.:|:..|.:|..||.|.|||||....:..|.:.::||.||:.|:.|.
  Rat   591 WSSYCRRKSLTETIYKNYFRIQLKPEQFSSYLTSPEVGFSSYELVATPSNTSRGFQRPVYLFHKA 655

  Fly  1114 DYTPNH 1119
             .:|:|
  Rat   656 -RSPSH 660

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bin3	NP_523626.2	PRK07764	<426..>559	CDD:236090	21/133 (16%)
		Cfa	783..>862	CDD:441831	32/78 (41%)
		Tam	824..>864	CDD:443282	19/39 (49%)
		Bin3	1004..1112	CDD:462022	54/107 (50%)
Mepce	NP_001094148.1	AdoMet_MTases	417..587	CDD:100107	70/221 (32%)
		Bin3	546..654	CDD:462022	54/107 (50%)