DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30431 and zgc:162948

DIOPT Version :9

Sequence 1:	NP_610211.1	Gene:	CG30431 / 35549	FlyBaseID:	FBgn0050431	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_001076388.1	Gene:	zgc:162948 / 797781	ZFINID:	ZDB-GENE-070424-46	Length:	288	Species:	Danio rerio

Alignment Length:	268	Identity:	81/268 - (30%)
Similarity:	122/268 - (45%)	Gaps:	36/268 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   136 ETVDFESLDFQDSSHSEHDIPSYWESSVDSGSLNTPHHQPETAELFAVEPPTPPESSEEPAPDAA 200
            |..:.:....:|....|.|:.:.    |:|........:.||..:|..:  ....|..|.:...|
Zfish    26 ELTELKPPKVEDEDEDEFDLMTI----VESIRAERTAERDETTSIFTCQ--VCAMSFSEQSDFDA 84

  Fly   201 EKPKMRRARPRQDNVKPKERKASGAVHPRSLHPCPECEKKFTRNFQLKLHMTAVHGMGEMRYQCE 265
            ......:.||                     :.|.:|.|:|.:...|..| ...| .|||...|:
Zfish    85 HIADYNKKRP---------------------YTCCQCGKEFRQIGSLVTH-KKFH-TGEMSLTCK 126

  Fly   266 ECRKNFASRHSLRYHVKSVHSTERPFGCQHCDRRFILRTQLLSHLRTHTGEAKPRIFECQRCSKS 330
            .|.|:|||.:|::.|::: |:.|||:.|.||.:.||......:|:|.|||| ||  |:|..|.||
Zfish   127 VCGKSFASIYSVKSHLRT-HTGERPYKCSHCGKAFISSGARCAHIRIHTGE-KP--FKCSLCGKS 187

  Fly   331 WPTKSDLRTHMRSHNPNMERPFKCDRCSKAFFTRGHLNSHLLVHTGEKPFACEYCDKCYQSVGNL 395
            :..:|.|.:|...|..  |:||||..|.::|..|..|.||.:||||...|:|:.|.|.:....||
Zfish   188 FTYRSALASHKTVHTG--EKPFKCSLCGRSFTYRSALASHKIVHTGVTSFSCKVCGKSFPFNCNL 250

  Fly   396 NNHMVRLH 403
            ..| :.:|
Zfish   251 ERH-INVH 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30431	NP_610211.1	zf-AD	11..82	CDD:285071
		C2H2 Zn finger	234..255	CDD:275368	6/20 (30%)
		C2H2 Zn finger	264..285	CDD:275368	8/20 (40%)
		C2H2 Zn finger	293..313	CDD:275368	7/19 (37%)
		zf-C2H2_8	305..373	CDD:292531	28/67 (42%)
		C2H2 Zn finger	324..344	CDD:275368	7/19 (37%)
		C2H2 Zn finger	354..374	CDD:275368	7/19 (37%)
		zf-H2C2_2	366..389	CDD:290200	11/22 (50%)
		C2H2 Zn finger	382..403	CDD:275368	6/20 (30%)
zgc:162948	NP_001076388.1	C2H2 Zn finger	69..89	CDD:275370	3/21 (14%)
		COG5048	<94..257	CDD:227381	67/192 (35%)
		C2H2 Zn finger	97..117	CDD:275368	6/20 (30%)
		C2H2 Zn finger	125..145	CDD:275368	8/20 (40%)
		zf-H2C2_2	137..160	CDD:290200	9/23 (39%)
		C2H2 Zn finger	153..173	CDD:275368	7/19 (37%)
		zf-H2C2_2	169..190	CDD:290200	13/23 (57%)
		C2H2 Zn finger	181..201	CDD:275368	7/19 (37%)
		zf-H2C2_2	193..218	CDD:290200	10/26 (38%)
		C2H2 Zn finger	209..229	CDD:275368	7/19 (37%)
		C2H2 Zn finger	237..257	CDD:275368	6/20 (30%)
		C2H2 Zn finger	265..283	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910