Protein Alignment CG30431 and ZFY

DIOPT Version :10

• Sequence 1: NP_610211.1
• Gene: CG30431 / 35549
• FlyBaseID: FBgn0050431
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: NP_003402.2
• Gene: ZFY / 7544
• HGNCID: 12870
• Length: 801
• Species: Homo sapiens
• Alignment Length: 336
• Identity: 80/336 - (23%)
• Similarity: 125/336 - (37%)
• Gaps: 106/336 - (31%)

  Fly   147 DSSHSEHDIPSYWESSVD---------SGSLNTPHHQPETAELFAVEPPTPPESSEEPAPDAAEK 202
            |....:..:|..|.::..         :|:.:...|..|:|.|..:               |.:|
Human   344 DEDEMKTFVPIAWAAAYGNNSDGIENRNGTASALLHIDESAGLGRL---------------AKQK 393

  Fly   203 PKMRRARPRQDNVKPKERKASGAV------HPRSLHPCPECEKKFTRNFQLKLHM---------- 251
            ||.:|        :|..|:...|:      ||.:::||..|.|||.....||.||
Human   394 PKKKR--------RPDSRQYQTAIIIGPDGHPLTVYPCMICGKKFKSRGFLKRHMKNHPEHLAKK 450

  Fly   252 --------------TAVH---------GMGEMRYQCEECRKNF---------------------- 271
                          .::|         ...|...:|:||.|:|
Human   451 KYHCTDCDYTTNKKISLHNHLESHKLTSKAEKAIECDECGKHFSHAGALFTHKMVHKEKGANKMH 515

  Fly   272 ---------ASRHSLRYHVKSVHSTERPFGCQHCDRRFILRTQLLSHLRTHTGEAKPRIFECQRC 327
                     |.:..|..|:.:|||...|..|..|.:.|...::|..|:|.|||| ||  ::||.|
Human   516 KCKFCEYETAEQGLLNRHLLAVHSKNFPHICVECGKGFRHPSELRKHMRIHTGE-KP--YQCQYC 577

  Fly   328 SKSWPTKSDLRTHMRSHNPNMERPFKCDRCSKAFFTRGHLNSHLLVHTGEKPFACEYCDKCYQSV 392
            .......|:|:||:::.: :.|.|||||.|...|.....:..|.|||...|...|.:||....:.
Human   578 EYRSADSSNLKTHIKTKH-SKEMPFKCDICLLTFSDTKEVQQHTLVHQESKTHQCLHCDHKSSNS 641

  Fly   393 GNLNNHMVRLH 403
            .:|..|::.:|
Human   642 SDLKRHVISVH 652

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30431	NP_610211.1	zf-AD	11..82	CDD:214871
		KREPA	<181..>257	CDD:483960	21/114 (18%)
		SFP1	<233..285	CDD:227516	20/115 (17%)
		C2H2 Zn finger	234..255	CDD:275368	9/44 (20%)
		C2H2 Zn finger	264..285	CDD:275368	8/51 (16%)
		C2H2 Zn finger	293..313	CDD:275368	6/19 (32%)
		C2H2 Zn finger	324..344	CDD:275368	7/19 (37%)
		C2H2 Zn finger	354..374	CDD:275368	6/19 (32%)
		zf-H2C2_2	366..389	CDD:463886	8/22 (36%)
		C2H2 Zn finger	382..403	CDD:275368	5/20 (25%)
ZFY	NP_003402.2	Zfx_Zfy_act	71..406	CDD:461400	15/84 (18%)
		COG5048	<417..592	CDD:227381	44/177 (25%)
		C2H2 Zn finger	423..443	CDD:275368	9/19 (47%)
		C2H2 Zn finger	454..478	CDD:275368	1/23 (4%)
		C2H2 Zn finger	486..506	CDD:275368	5/19 (26%)
		COG5048	539..>676	CDD:227381	40/118 (34%)
		C2H2 Zn finger	546..566	CDD:275368	6/19 (32%)
		zf-H2C2_2	558..582	CDD:463886	12/26 (46%)
		C2H2 Zn finger	574..593	CDD:275368	7/18 (39%)
		C2H2 Zn finger	603..652	CDD:275368	14/48 (29%)
		C2H2 Zn finger	660..680	CDD:275368
		zf-C2H2	715..737	CDD:395048
		C2H2 Zn finger	717..737	CDD:275368
		zf-H2C2_2	729..753	CDD:463886
		C2H2 Zn finger	745..766	CDD:275368
		C2H2 Zn finger	774..794	CDD:275368