Protein Alignment CG30431 and ZFX

DIOPT Version :10

• Sequence 1: NP_610211.1
• Gene: CG30431 / 35549
• FlyBaseID: FBgn0050431
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: NP_001317256.1
• Gene: ZFX / 7543
• HGNCID: 12869
• Length: 844
• Species: Homo sapiens
• Alignment Length: 275
• Identity: 72/275 - (26%)
• Similarity: 108/275 - (39%)
• Gaps: 82/275 - (29%)

  Fly   199 AAEKPKMRRARPRQDNVKPKERKASGAV------HPRSLHPCPECEKKFTRNFQLKLHM------ 251
            |.:|||.||        :|..|:...|:      ||.:::||..|.|||.....||.||
Human   433 AKQKPKKRR--------RPDSRQYQTAIIIGPDGHPLTVYPCMICGKKFKSRGFLKRHMKNHPEH 489

  Fly   252 ------------------TAVH---------GMGEMRYQCEECRKNF------------------ 271
                              .::|         ...|...:|:||.|:|
Human   490 LAKKKYRCTDCDYTTNKKISLHNHLESHKLTSKAEKAIECDECGKHFSHAGALFTHKMVHKEKGA 554

  Fly   272 -------------ASRHSLRYHVKSVHSTERPFGCQHCDRRFILRTQLLSHLRTHTGEAKPRIFE 323
                         |.:..|..|:.:|||...|..|..|.:.|...::|..|:|.|||| ||  ::
Human   555 NKMHKCKFCEYETAEQGLLNRHLLAVHSKNFPHICVECGKGFRHPSELKKHMRIHTGE-KP--YQ 616

  Fly   324 CQRCSKSWPTKSDLRTHMRSHNPNMERPFKCDRCSKAFFTRGHLNSHLLVHTGEKPFACEYCDKC 388
            ||.|.......|:|:||:::.: :.|.|||||.|...|.....:..|.|:|...|...|.:||..
Human   617 CQYCEYRSADSSNLKTHVKTKH-SKEMPFKCDICLLTFSDTKEVQQHALIHQESKTHQCLHCDHK 680

  Fly   389 YQSVGNLNNHMVRLH 403
            ..:..:|..|::.:|
Human   681 SSNSSDLKRHIISVH 695

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30431	NP_610211.1	zf-AD	11..82	CDD:214871
		KREPA	<181..>257	CDD:483960	22/96 (23%)
		SFP1	<233..285	CDD:227516	20/115 (17%)
		C2H2 Zn finger	234..255	CDD:275368	9/44 (20%)
		C2H2 Zn finger	264..285	CDD:275368	8/51 (16%)
		C2H2 Zn finger	293..313	CDD:275368	6/19 (32%)
		C2H2 Zn finger	324..344	CDD:275368	7/19 (37%)
		C2H2 Zn finger	354..374	CDD:275368	6/19 (32%)
		zf-H2C2_2	366..389	CDD:463886	7/22 (32%)
		C2H2 Zn finger	382..403	CDD:275368	5/20 (25%)
ZFX	NP_001317256.1	Zfx_Zfy_act	109..449	CDD:461400	8/23 (35%)
		ROS_MUCR	<416..>496	CDD:473244	21/70 (30%)
		C2H2 Zn finger	466..486	CDD:275368	9/19 (47%)
		C2H2 Zn finger	497..521	CDD:275368	1/23 (4%)
		C2H2 Zn finger	529..549	CDD:275368	5/19 (26%)
		COG5048	582..>719	CDD:227381	39/118 (33%)
		C2H2 Zn finger	589..609	CDD:275368	6/19 (32%)
		C2H2 Zn finger	617..636	CDD:275368	7/18 (39%)
		C2H2 Zn finger	674..695	CDD:275368	5/20 (25%)
		C2H2 Zn finger	703..723	CDD:275368
		zf-C2H2	758..780	CDD:395048
		C2H2 Zn finger	760..780	CDD:275368
		zf-H2C2_2	772..796	CDD:463886
		C2H2 Zn finger	788..809	CDD:275368
		C2H2 Zn finger	817..837	CDD:275368