DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30431 and CG6791

DIOPT Version :9

Sequence 1:	NP_610211.1	Gene:	CG30431 / 35549	FlyBaseID:	FBgn0050431	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_650090.1	Gene:	CG6791 / 41391	FlyBaseID:	FBgn0037918	Length:	1243	Species:	Drosophila melanogaster

Alignment Length:	458	Identity:	93/458 - (20%)
Similarity:	138/458 - (30%)	Gaps:	172/458 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 DVICDLCLRRLHDARDFQRRCEHSEQVLRMRHEHWKHTVAVGDALALDDVLECLEREVGSLEGPM 118
            |::|:..|:.|.|                   .|::|       |.....|:||          :
  Fly   800 DIVCNSKLKGLQD-------------------HHFRH-------LPYRLYLKCL----------I 828

  Fly   119 SVPLQASKP--VAHV----------APLMETVDFESLD-FQDSSHSEHDIPSYWESSVDSGSLNT 170
            .......||  .||:          .|.|.|...:.|. ::|:|.....:||
  Fly   829 CGTCYNHKPNIAAHLRARHSIFDRETPTMITKPKQVLGRYKDNSRENPKLPS------------- 880

  Fly   171 PHHQPETAELFAVEPPTPPESSEEPAPDAAEK-----PKMRRARPRQDNVKPKERKASGAVHPRS 230
                |..|...|..||:||..|...|..|:.:     |....|||...|..........||....
  Fly   881 ----PPPAPALAPAPPSPPACSSSAAASASSRSLKPQPGGLPARPAGLNTLEDSISYHNAVDLDF 941

  Fly   231 L-HPCPECEKKFTRNFQLKLHMTAVHGMGEM-----------RYQCEECRKNFASRHS------L 277
            : :.||:|.:.|..:...:.|:...|.....           .|.|.||.|.....|:      |
  Fly   942 ITYFCPKCNQNFDSHAFWRKHIVEQHNFNSREGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQL 1006

  Fly   278 RYHVKSVHSTERPFGCQHCDRRFILRTQLLSHLRTHTGEAKPRIFECQRCSKSWPTKSDLRTHMR 342
            :.| |..|...|.|.|..|...|:.:.....||...|          .||        |.|.|..
  Fly  1007 QSH-KFRHLPHRSFKCLTCGGEFVRKQMFFKHLNRDT----------NRC--------DNRPHRE 1052

  Fly   343 SHNPNMERP--------FKCDRCSKAFFT------RGHLNSH------LLVH---TGEKPFACEY 384
            ..:...::.        ..|.:|...|.|      |.|:|.|      .|:|   .||..:.|:.
  Fly  1053 FDDDEPDQDTLLSTIYHLTCPQCGDNFKTHNKKEWREHINDHHGLTKLELLHMTKVGEDVYRCQD 1117

  Fly   385 CDK----------------------------CYQS-------VGNLNN------HMVRLHADIIE 408
            ||:                            |.||       ||.|::      |:.:.|..:.:
  Fly  1118 CDEELETNRQWVLQFHRFQHLPHAAYIRCKLCKQSSADGADAVGELHSLRELQQHIRKHHPGLGD 1182

  Fly   409 AQL 411
            |::
  Fly  1183 AEM 1185

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30431	NP_610211.1	zf-AD	11..82	CDD:285071	5/27 (19%)
		C2H2 Zn finger	234..255	CDD:275368	5/20 (25%)
		C2H2 Zn finger	264..285	CDD:275368	8/26 (31%)
		C2H2 Zn finger	293..313	CDD:275368	5/19 (26%)
		zf-C2H2_8	305..373	CDD:292531	16/87 (18%)
		C2H2 Zn finger	324..344	CDD:275368	5/19 (26%)
		C2H2 Zn finger	354..374	CDD:275368	9/31 (29%)
		zf-H2C2_2	366..389	CDD:290200	10/59 (17%)
		C2H2 Zn finger	382..403	CDD:275368	10/61 (16%)
CG6791	NP_650090.1	C2H2 Zn finger	167..188	CDD:275368
		C2H2 Zn finger	208..230	CDD:275368
		C2H2 Zn finger	235..256	CDD:275368
		C2H2 Zn finger	516..532	CDD:275368
		C2H2 Zn finger	557..580	CDD:275368
		C2H2 Zn finger	589..609	CDD:275368
		COG5236	<939..>1096	CDD:227561	37/175 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100