DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30431 and CG8478

DIOPT Version :9

Sequence 1:	NP_610211.1	Gene:	CG30431 / 35549	FlyBaseID:	FBgn0050431	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_001163576.1	Gene:	CG8478 / 41194	FlyBaseID:	FBgn0037746	Length:	576	Species:	Drosophila melanogaster

Alignment Length:	351	Identity:	80/351 - (22%)
Similarity:	121/351 - (34%)	Gaps:	118/351 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   134 LMETVDFESLDFQDSSHSE--HDIPSYWESSVD-------SGSLNTPHHQPETAEL-FAVEPPTP 188
            :||::|...:|.::::..|  ....|...||||       :.:|.|.....:...| .|.:.|.|
  Fly   130 IMESIDLTQIDDKENTQPEGCGGDNSTLSSSVDVTANTVKANTLKTGDATMDNVSLQEAAKTPAP 194

  Fly   189 ---------------PESSEE-----PAPDAAEKPK--------------MRRARPRQDNVKP-- 217
                           .|.|.|     .:|..|||..              .:..:...|:|||
  Fly   195 SQVYPLSANVVLENITEVSNEGVSMLVSPAGAEKEVAHVNEVVNEVSELIAKALKISADSVKPAT 259

  Fly   218 --------KERKA-----SGAVHP---RSLHPCPECEKKFTRNFQLKLHMTAV------------ 254
                    |:|::     |||..|   ||..|....|   ||.:..|..|:.|
  Fly   260 SKLKVEAGKKRQSMSSTYSGAALPRPRRSYLPTTTAE---TRTYSFKQRMSVVVKTTLNSPARKR 321

  Fly   255 ---HGMGEMRYQCEECRKNFASRHSLR--YHVKSVHSTE----RPFGCQHCDRRFILRTQLLSHL 310
               .|:...|..|....|  .::.|:|  ..|.||.|.|    :|                   .
  Fly   322 SVGGGVSLSRRSCLPVSK--LTKSSIRKSLAVTSVRSPEKIASKP-------------------A 365

  Fly   311 RTHTGEAKPRIFECQRCSKSWPTKSDLRTHMRSHNPNMERPFKCDRCSKAFFTRGHLNSHLLVHT 375
            :|.|.....::|.|:.||.::..||.|..|||.|:|          ......|...|||: .|..
  Fly   366 KTSTKSIPEKVFSCKNCSTTFRVKSLLDVHMRMHDP----------VDNGANTLKRLNSN-PVAA 419

  Fly   376 GEKPFACEYCDKCYQSVGNLNNHMVR 401
            |.....|::|||.:.....|:.|:::
  Fly   420 GVSKNRCKFCDKNFALERALHIHLMQ 445

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30431	NP_610211.1	zf-AD	11..82	CDD:285071
		C2H2 Zn finger	234..255	CDD:275368	6/35 (17%)
		C2H2 Zn finger	264..285	CDD:275368	6/22 (27%)
		C2H2 Zn finger	293..313	CDD:275368	0/19 (0%)
		zf-C2H2_8	305..373	CDD:292531	18/67 (27%)
		C2H2 Zn finger	324..344	CDD:275368	9/19 (47%)
		C2H2 Zn finger	354..374	CDD:275368	4/19 (21%)
		zf-H2C2_2	366..389	CDD:290200	9/22 (41%)
		C2H2 Zn finger	382..403	CDD:275368	6/20 (30%)
CG8478	NP_001163576.1	zf-C2H2	377..399	CDD:278523	10/21 (48%)
		C2H2 Zn finger	379..399	CDD:275368	9/19 (47%)
		C2H2 Zn finger	426..444	CDD:275368	6/17 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100