DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30431 and CG10543

DIOPT Version :9

Sequence 1:	NP_610211.1	Gene:	CG30431 / 35549	FlyBaseID:	FBgn0050431	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_001369100.1	Gene:	CG10543 / 37379	FlyBaseID:	FBgn0034570	Length:	1666	Species:	Drosophila melanogaster

Alignment Length:	406	Identity:	82/406 - (20%)
Similarity:	150/406 - (36%)	Gaps:	113/406 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 HSEQVLRMRHEHWKHTVAVGDALALDDVLECLER--EVGSLEGPMSVPLQASKPVAHVAPLMETV 138
            |..|::.|..:..:|..::.::..: ..|..|..  :..::.|.::..|:              :
  Fly   609 HQRQMMMMPEDFPQHGASMMNSRQM-PALAALSNLGDTPAMSGQLNSSLE--------------L 658

  Fly   139 DFESL----DFQDSSHSEHDIPSYWESSVDSGSLNTPHHQPETAELFAVEPP------------- 186
            |...|    |..|..|...::.:..:..:|.||.::...|         .||
  Fly   659 DDNDLSADEDDDDLDHDLDELDAAKQQLIDGGSSSSTSLQ---------APPSQHGSGSGGSGGQ 714

  Fly   187 TPPESSEEPAPDAAEKPK-MRRARPRQDNVKPKERKASGAVHP---------------------R 229
            ||....::|:.:....|| .|:.:...|:.|         :||                     |
  Fly   715 TPGSKKDKPSYNCLLCPKSYRKRKSLLDHYK---------MHPGYCHDCGQRNGNTLEEIIHHNR 770

  Fly   230 SLH------PCPECEKKFTRNFQLKLHMTAVHGMGEMR-------------------YQ------ 263
            ::|      .|..|.:.::|..|...|:.: |...|::                   ::
  Fly   771 TMHVKEFPFVCETCGESYSRKQQFHAHVES-HNKKEIKTFPCGECGLKFPQKKLQQHFEETGHKA 834

  Fly   264 ----CEECRKNFASRHSLRYHVKSVHSTERPFGCQHCDRRFILRTQLLSHLRTHTGEAKPRIFEC 324
                ||.|.:.|.|:::|..|:..||..:..|.|..|..||.|:..|..|::.||...:|  :.|
  Fly   835 DGAICEVCGEEFQSKNALYQHIIRVHKRDNFFECHICHNRFTLKANLERHVQLHTEIKRP--YVC 897

  Fly   325 QRCSKSWPTKSDLRTHMRSHNPNMERPFKCDRCSKAFFTRGHLNSHLLVHTGEKPFACEYCDKCY 389
            ..|..|:.|...|:.|..:.:.::.. .||..|.|.|.:...|..||..|:.|:|..|.|||:.:
  Fly   898 DLCGSSYFTYPALKEHYSNAHVDVSE-CKCTLCGKRFGSAKSLQRHLPSHSEERPHCCNYCDQTF 961

  Fly   390 QSVGNLNNHMVRLHAD 405
            :...:|..|...:|.:
  Fly   962 KWKTHLVRHKQTMHGN 977

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30431	NP_610211.1	zf-AD	11..82	CDD:285071	2/5 (40%)
		C2H2 Zn finger	234..255	CDD:275368	5/20 (25%)
		C2H2 Zn finger	264..285	CDD:275368	7/20 (35%)
		C2H2 Zn finger	293..313	CDD:275368	7/19 (37%)
		zf-C2H2_8	305..373	CDD:292531	19/67 (28%)
		C2H2 Zn finger	324..344	CDD:275368	6/19 (32%)
		C2H2 Zn finger	354..374	CDD:275368	7/19 (37%)
		zf-H2C2_2	366..389	CDD:290200	10/22 (45%)
		C2H2 Zn finger	382..403	CDD:275368	6/20 (30%)
CG10543	NP_001369100.1	C2H2 Zn finger	727..747	CDD:275368	5/28 (18%)
		C2H2 Zn finger	751..773	CDD:275368	1/21 (5%)
		C2H2 Zn finger	781..801	CDD:275368	5/20 (25%)
		PHA00733	<804..860	CDD:177301	8/55 (15%)
		C2H2 Zn finger	811..827	CDD:275368	0/15 (0%)
		C2H2 Zn finger	839..860	CDD:275368	7/20 (35%)
		C2H2 Zn finger	868..888	CDD:275368	7/19 (37%)
		C2H2 Zn finger	897..913	CDD:275368	5/15 (33%)
		C2H2 Zn finger	926..946	CDD:275368	7/19 (37%)
		C2H2 Zn finger	954..975	CDD:275368	6/20 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100