DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30431 and crol

DIOPT Version :9

Sequence 1:	NP_610211.1	Gene:	CG30431 / 35549	FlyBaseID:	FBgn0050431	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_001245993.1	Gene:	crol / 34592	FlyBaseID:	FBgn0020309	Length:	962	Species:	Drosophila melanogaster

Alignment Length:	198	Identity:	77/198 - (38%)
Similarity:	111/198 - (56%)	Gaps:	13/198 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   211 RQDNVKPKERKASGAVHPRSLHPCPECEKKFTRNFQLKLHMTAVHGMGEMRYQCEECRKNFASRH 275
            |::::....|:.:|    .|.|.|..|:|.|||...|..|: .:| .|:..::||.|:|.|..:.
  Fly   540 RKEHLTNHVRQHTG----DSPHRCSYCKKTFTRKEHLTNHV-RLH-TGDSPHKCEYCQKTFTRKE 598

  Fly   276 SLRYHVKSVHSTERPFGCQHCDRRFILRTQLLSHL-RTHTGEAKPRIFECQRCSKSWPTKSDLRT 339
            .|..|::. ||::.|..|..|::.|..:..|::|: |.|||:   |.|.|:.|.||:|.|.:|..
  Fly   599 HLNNHMRQ-HSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGD---RPFTCETCGKSFPLKGNLLF 659

  Fly   340 HMRSH--NPNMERPFKCDRCSKAFFTRGHLNSHLLVHTGEKPFACEYCDKCYQSVGNLNNHMVRL 402
            |.|||  ...|||||.|::|.|.|..:|||.||:..|:||||.||..|.|.:...|||..||...
  Fly   660 HQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMN 724

  Fly   403 HAD 405
            |.|
  Fly   725 HPD 727

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30431	NP_610211.1	zf-AD	11..82	CDD:285071
		C2H2 Zn finger	234..255	CDD:275368	8/20 (40%)
		C2H2 Zn finger	264..285	CDD:275368	7/20 (35%)
		C2H2 Zn finger	293..313	CDD:275368	6/20 (30%)
		zf-C2H2_8	305..373	CDD:292531	33/70 (47%)
		C2H2 Zn finger	324..344	CDD:275368	9/19 (47%)
		C2H2 Zn finger	354..374	CDD:275368	9/19 (47%)
		zf-H2C2_2	366..389	CDD:290200	13/22 (59%)
		C2H2 Zn finger	382..403	CDD:275368	8/20 (40%)
crol	NP_001245993.1	C2H2 Zn finger	223..243	CDD:275368
		C2H2 Zn finger	251..271	CDD:275368
		C2H2 Zn finger	279..299	CDD:275368
		COG5048	300..723	CDD:227381	75/192 (39%)
		C2H2 Zn finger	307..327	CDD:275368
		C2H2 Zn finger	335..355	CDD:275368
		C2H2 Zn finger	363..383	CDD:275368
		C2H2 Zn finger	391..411	CDD:275368
		C2H2 Zn finger	419..439	CDD:275368
		C2H2 Zn finger	447..467	CDD:275368
		C2H2 Zn finger	475..495	CDD:275368
		C2H2 Zn finger	503..523	CDD:275368
		C2H2 Zn finger	531..551	CDD:275368	2/10 (20%)
		C2H2 Zn finger	559..579	CDD:275368	8/20 (40%)
		C2H2 Zn finger	587..607	CDD:275368	7/20 (35%)
		C2H2 Zn finger	615..636	CDD:275368	6/20 (30%)
		C2H2 Zn finger	644..664	CDD:275368	9/19 (47%)
		C2H2 Zn finger	676..696	CDD:275368	9/19 (47%)
		C2H2 Zn finger	704..722	CDD:275368	7/17 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453398
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930