DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30431 and let-391

DIOPT Version :9

Sequence 1:	NP_610211.1	Gene:	CG30431 / 35549	FlyBaseID:	FBgn0050431	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_491744.3	Gene:	let-391 / 182953	WormBaseID:	WBGene00006492	Length:	453	Species:	Caenorhabditis elegans

Alignment Length:	206	Identity:	55/206 - (26%)
Similarity:	86/206 - (41%)	Gaps:	19/206 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   210 PRQDNVKPKERKASGAVHPRSLHPC-PECEKKFTRNFQ----LKLHMTAVHGMGEMRYQCEECRK 269
            |...:..|.:.::|.....:|::|. .|.||....|.:    :...:..|....:.....||..|
Worm   188 PSTSSSSPSQFQSSNQTTKQSIYPSEKEMEKAAISNARIDDVINTVLARVLAPIDEEIPIEEPEK 252

  Fly   270 NFASRHSLRYHVKSVHSTERPFGCQHCDRRFILRTQLLSHLRTHTGEAKPRIFECQRCSKSWPTK 334
                ....|.::.:..:|...  |..|.......:::..|:|||||| ||  |||..|..|....
Worm   253 ----APQKRAYISNRRATLAQ--CNICGLMLKHPSKIADHIRTHTGE-KP--FECGECGLSLSKA 308

  Fly   335 SDLRTHMRSHNPNMERPFKCD-RCSKAFFTRGHLNSH-LLVHTGEKPFAC--EYCDKCYQSVGNL 395
            |.|:.|:|..:.. ||||:|. ||..:|.|......| :.||||.|.:.|  :.|:..:.....|
Worm   309 SSLKVHIRRMHTG-ERPFECTWRCGLSFVTDSVRKEHEMTVHTGIKRYTCVVKGCNAVFARRVYL 372

  Fly   396 NNHMVRLHADI 406
            ..|....|.::
Worm   373 MRHRKNAHPEL 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30431	NP_610211.1	zf-AD	11..82	CDD:285071
		C2H2 Zn finger	234..255	CDD:275368	4/25 (16%)
		C2H2 Zn finger	264..285	CDD:275368	4/20 (20%)
		C2H2 Zn finger	293..313	CDD:275368	4/19 (21%)
		zf-C2H2_8	305..373	CDD:292531	28/69 (41%)
		C2H2 Zn finger	324..344	CDD:275368	7/19 (37%)
		C2H2 Zn finger	354..374	CDD:275368	6/21 (29%)
		zf-H2C2_2	366..389	CDD:290200	8/25 (32%)
		C2H2 Zn finger	382..403	CDD:275368	4/22 (18%)
let-391	NP_491744.3	C2H2 Zn finger	59..79	CDD:275368
		zf-H2C2_2	73..96	CDD:290200
		C2H2 Zn finger	87..108	CDD:275368
		C2H2 Zn finger	116..137	CDD:275368
		C2H2 Zn finger	270..290	CDD:275368	4/19 (21%)
		zf-H2C2_2	286..304	CDD:290200	13/20 (65%)
		C2H2 Zn finger	298..319	CDD:275368	7/20 (35%)
		C2H2 Zn finger	327..347	CDD:275368	6/19 (32%)
		C2H2 Zn finger	357..377	CDD:275368	4/19 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100