DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30431 and unc-98

DIOPT Version :9

Sequence 1:	NP_610211.1	Gene:	CG30431 / 35549	FlyBaseID:	FBgn0050431	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_509284.2	Gene:	unc-98 / 181020	WormBaseID:	WBGene00006827	Length:	310	Species:	Caenorhabditis elegans

Alignment Length:	282	Identity:	69/282 - (24%)
Similarity:	108/282 - (38%)	Gaps:	46/282 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   136 ETVDFESL----DFQDSSHSEHDIPSYWESSVDSGSLNTPHHQPETAELFAVEPPT--------- 187
            |..|||.|    |....|...:::....|:...:|..:...::.:..|:..|..||
Worm    12 ERDDFEELMNACDLAKMSVKNNEMVHGLETFGINGESSENGNKEKPKEIMKVVAPTVEAYVGSSS 76

  Fly   188 --PPESSEEPAPDAAEKPKMRRARPRQDNVKPKERKASGAVHPRSLHPCPECEKKFTRNFQLKLH 250
              .|..|...|.|.:::.::     |||... .::..:|.|    .:.|..|...|.....|:.|
Worm    77 AQTPTKSSGGALDGSDQQEV-----RQDGTS-VQKDDNGFV----FYKCRFCGLTFNFMNTLRAH 131

  Fly   251 MTAVHGMGEMRYQCEECRKNFASRHSLRYHVKSVHSTERPFGCQHCDRRFILRTQLLSHLRTHTG 315
             ..:|.:.: .|.|.:|..:|.....|.||. :.||....:.|: |.|.|...|::|.|  .||.
Worm   132 -ERIHDVSQ-PYVCGKCGDSFEFACQLEYHA-AQHSEIDGYKCE-CGRTFFSYTEMLYH--KHTD 190

  Fly   316 EAKPRIFECQRCSKSWPTKSDLRTHMRSHNPNMERPFKCDRCSKAFFTRGHLNSH-LLVHTG--E 377
            :....|        ..|..:.::...:...|..|:    |....||.|.|:...| |.|:..  .
Worm   191 DPLELI--------GAPETTTIKVSKKRVLPVSEQ----DLPQPAFVTEGYEPKHPLRVYNDVRS 243

  Fly   378 KPFACEYCDKCYQSVGNLNNHM 399
            ||:.||||.|.|.....|..||
Worm   244 KPYICEYCSKSYSDSRGLAYHM 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30431	NP_610211.1	zf-AD	11..82	CDD:285071
		C2H2 Zn finger	234..255	CDD:275368	5/20 (25%)
		C2H2 Zn finger	264..285	CDD:275368	6/20 (30%)
		C2H2 Zn finger	293..313	CDD:275368	7/19 (37%)
		zf-C2H2_8	305..373	CDD:292531	15/68 (22%)
		C2H2 Zn finger	324..344	CDD:275368	1/19 (5%)
		C2H2 Zn finger	354..374	CDD:275368	7/20 (35%)
		zf-H2C2_2	366..389	CDD:290200	10/25 (40%)
		C2H2 Zn finger	382..403	CDD:275368	9/18 (50%)
unc-98	NP_509284.2	C2H2 Zn finger	115..135	CDD:275368	5/20 (25%)
		C2H2 Zn finger	143..163	CDD:275368	6/20 (30%)
		SFP1	<169..268	CDD:227516	32/112 (29%)
		C2H2 Zn finger	171..189	CDD:275368	7/20 (35%)
		C2H2 Zn finger	248..268	CDD:275368	9/18 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100