DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30431 and Y111B2A.10

DIOPT Version :9

Sequence 1:	NP_610211.1	Gene:	CG30431 / 35549	FlyBaseID:	FBgn0050431	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_499640.1	Gene:	Y111B2A.10 / 176678	WormBaseID:	WBGene00013734	Length:	430	Species:	Caenorhabditis elegans

Alignment Length:	379	Identity:	77/379 - (20%)
Similarity:	130/379 - (34%)	Gaps:	105/379 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   125 SKPVAHVAPLMETVDFESLDFQDSSHSEHDIPSYWESSVDSGSLNTPHHQPETAELF--AVEPPT 187
            :|.|.....|:|.::||..|.:....:| ::.|..|...|. .:..|:.:.:..:..  .:|...
Worm    36 NKNVNEFQKLIEELEFEPEDRRVPEVAE-EVESEDEEEEDV-QIKYPYERKDAYQDLQERIERRL 98

  Fly   188 PPESSEEPAPDAAEKPKMRRARPRQDNVKPKERKASGAVHPR---SLHPCPECEKKFTRNFQLKL 249
            .....|:....|.|...:.|....|..|:.|::.....:.|.   |:..|..|.|.|.....|::
Worm    99 NDSGDEKLEQKAKELQSLIRMSQSQWKVEQKQQLEDSLLKPHTAGSIFTCVMCSKAFPNAEALQI 163

  Fly   250 HMTAVHGMGEMRYQCEECRKNFASRHSLRYHVKSVHSTERPFGCQHCDRRFILRTQLLSHL---- 310
            |...||.:..::::|:.|.|.:..:.:|..|: ::|..|  ..|.:|...|.....|.||:
Worm   164 HTDQVHDLSRLKHRCKLCGKAYKRKKNLDAHM-ALHLKE--IQCDNCSLVFQSEKSLQSHIIRHH 225

  Fly   311 --------------------------RTHTGEAKPR--IFE------------------------ 323
                                      :||....|.|  |.|
Worm   226 QEDADELEVWKAPCSICKELFPSTSVKTHEWYCKNREKIIEKQRVSKILKVQSLPSSPALSTVSY 290

  Fly   324 ---------------------CQRCSKSWPTKSDLRTHM-RSH-----NPNM-----------ER 350
                                 ||.|.:|:.::..:..|: |.|     :||:           :.
Worm   291 ASFSSCQPGPITSPVSYRDKSCQVCGESFASRQSMLRHVGRKHPDAKNDPNVTAVRYISAESPKH 355

  Fly   351 PFKCDRCSKAFFTRGHLNSH-LLVHTGEKPFACEYCDKCYQSVGNLNNHMVRLH 403
            |:.|..|.|.|.|...|::| ..||:....|.|..|.|.|.....|..|:.|:|
Worm   356 PYACIECGKRFTTVTALSTHKARVHSQSNRFECTICHKSYPVPSELRKHIKRVH 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30431	NP_610211.1	zf-AD	11..82	CDD:285071
		C2H2 Zn finger	234..255	CDD:275368	6/20 (30%)
		C2H2 Zn finger	264..285	CDD:275368	5/20 (25%)
		C2H2 Zn finger	293..313	CDD:275368	6/49 (12%)
		zf-C2H2_8	305..373	CDD:292531	26/162 (16%)
		C2H2 Zn finger	324..344	CDD:275368	6/20 (30%)
		C2H2 Zn finger	354..374	CDD:275368	7/20 (35%)
		zf-H2C2_2	366..389	CDD:290200	8/23 (35%)
		C2H2 Zn finger	382..403	CDD:275368	7/20 (35%)
Y111B2A.10	NP_499640.1	C2H2 Zn finger	148..169	CDD:275368	6/20 (30%)
		zf-C2H2_8	151..221	CDD:292531	19/72 (26%)
		C2H2 Zn finger	178..198	CDD:275368	5/20 (25%)
		C2H2 Zn finger	204..224	CDD:275368	6/19 (32%)
		C2H2 Zn finger	312..333	CDD:275368	6/20 (30%)
		C2H2 Zn finger	359..380	CDD:275368	7/20 (35%)
		C2H2 Zn finger	388..409	CDD:275368	7/20 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24409
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010