DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30431 and ZNF664

DIOPT Version :9

Sequence 1:	NP_610211.1	Gene:	CG30431 / 35549	FlyBaseID:	FBgn0050431	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_001191227.1	Gene:	ZNF664 / 144348	HGNCID:	25406	Length:	261	Species:	Homo sapiens

Alignment Length:	172	Identity:	64/172 - (37%)
Similarity:	91/172 - (52%)	Gaps:	9/172 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   232 HPCPECEKKFTRNFQLKLHMTAVHGMGEMRYQCEECRKNFASRHSLRYHVKSVHSTERPFGCQHC 296
            |.|.:|:|.|....:|.:|..  ...||..|:|::|.|:|::...|..| |.:|:.|:|:.|..|
Human    31 HKCDKCDKGFFHISELHIHWR--DHTGEKVYKCDDCGKDFSTTTKLNRH-KKIHTVEKPYKCYEC 92

  Fly   297 DRRFILRTQLLSHLRTHTGEAKPRIFECQRCSKSWPTKSDLRTHMRSHNPNMERPFKCDRCSKAF 361
            .:.|...:.|..|:|.|||| ||  :.|..|.:.:...|:|..|.|.|..  |:||||:.|.|||
Human    93 GKAFNWSSHLQIHMRVHTGE-KP--YVCSECGRGFSNSSNLCMHQRVHTG--EKPFKCEECGKAF 152

  Fly   362 FTRGHLNSHLLVHTGEKPFACEYCDKCYQSVGNLNNHMVRLH 403
            .....|..|..|||||||:.|..|.|.:....:|..|. |:|
Human   153 RHTSSLCMHQRVHTGEKPYKCYECGKAFSQSSSLCIHQ-RVH 193

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30431	NP_610211.1	zf-AD	11..82	CDD:285071
		C2H2 Zn finger	234..255	CDD:275368	6/20 (30%)
		C2H2 Zn finger	264..285	CDD:275368	7/20 (35%)
		C2H2 Zn finger	293..313	CDD:275368	6/19 (32%)
		zf-C2H2_8	305..373	CDD:292531	27/67 (40%)
		C2H2 Zn finger	324..344	CDD:275368	6/19 (32%)
		C2H2 Zn finger	354..374	CDD:275368	7/19 (37%)
		zf-H2C2_2	366..389	CDD:290200	12/22 (55%)
		C2H2 Zn finger	382..403	CDD:275368	6/20 (30%)
ZNF664	NP_001191227.1	C2H2 Zn finger	5..25	CDD:275368
		C2H2 Zn finger	33..53	CDD:275368	6/21 (29%)
		C2H2 Zn finger	61..81	CDD:275368	7/20 (35%)
		zf-H2C2_2	74..97	CDD:404364	8/23 (35%)
		C2H2 Zn finger	89..109	CDD:275368	6/19 (32%)
		COG5048	<94..256	CDD:227381	42/106 (40%)
		C2H2 Zn finger	117..137	CDD:275368	6/19 (32%)
		C2H2 Zn finger	145..165	CDD:275368	7/19 (37%)
		C2H2 Zn finger	173..193	CDD:275368	6/20 (30%)
		C2H2 Zn finger	201..221	CDD:275368
		C2H2 Zn finger	229..249	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7426
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.950