DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30431 and znf1077

DIOPT Version :9

Sequence 1:	NP_610211.1	Gene:	CG30431 / 35549	FlyBaseID:	FBgn0050431	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_001108580.1	Gene:	znf1077 / 100141492	ZFINID:	ZDB-GENE-080218-11	Length:	332	Species:	Danio rerio

Alignment Length:	273	Identity:	80/273 - (29%)
Similarity:	121/273 - (44%)	Gaps:	58/273 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   173 HQPETAELFAVEPPTPPESSEEPAPDAAEKPKMRRAR------------PRQDNVKPKERKASGA 225
            ||..|.:    |.||..|.:     .:...|:..::.            .|:.|::...:..:|
Zfish    21 HQETTTD----EKPTLTEKT-----SSCGGPRKSKSACNFTCLQCGNCFTRKHNLQVHMKVHTG- 75

  Fly   226 VHPRSLHPCPECEKKFTRNFQLKLHMTAVHGMGEMRYQCEECRKNFASRHSLRYHVKSVHSTERP 290
               :..:.||:|.|.|.:|..||:|| ..| .||..|.|::|.:.|.:..:...|:: :|:.|||
Zfish    76 ---QKPYSCPQCGKSFKQNGYLKVHM-RTH-TGERCYTCQQCGQRFYTTGNFAQHMR-IHTGERP 134

  Fly   291 FGCQHCDRRFILRTQLLSHLRTHTGEAKP--------------------------RIFECQRCSK 329
            :.|..|.:.......|.:|:|.||.| ||                          |||.|.:|.|
Zfish   135 YTCLQCGKSLYQSANLAAHMRIHTVE-KPYSCIQCGKSFKQNSTLEAHIRAHNDGRIFTCPQCGK 198

  Fly   330 SWPTKSDLRTHMRSHNPNMERPFKCDRCSKAFFTRGHLNSHLLVHTGEKPFACEYCDKCYQSVGN 394
            |:..|.||..|.|.|..  |:|:.|..|.|.|..:..||.|::.|||||||.|..|.:.:.:..:
Zfish   199 SFAQKQDLEIHTRIHTG--EKPYTCTECGKRFRFKSTLNQHMISHTGEKPFTCAQCGRSFTTKSS 261

  Fly   395 LNNHMVRLHADII 407
            |.||| .:|...|
Zfish   262 LMNHM-NVHTGTI 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30431	NP_610211.1	zf-AD	11..82	CDD:285071
		C2H2 Zn finger	234..255	CDD:275368	10/20 (50%)
		C2H2 Zn finger	264..285	CDD:275368	4/20 (20%)
		C2H2 Zn finger	293..313	CDD:275368	5/19 (26%)
		zf-C2H2_8	305..373	CDD:292531	30/93 (32%)
		C2H2 Zn finger	324..344	CDD:275368	9/19 (47%)
		C2H2 Zn finger	354..374	CDD:275368	7/19 (37%)
		zf-H2C2_2	366..389	CDD:290200	12/22 (55%)
		C2H2 Zn finger	382..403	CDD:275368	6/20 (30%)
znf1077	NP_001108580.1	C2H2 Zn finger	53..73	CDD:275368	2/19 (11%)
		zf-H2C2_2	65..90	CDD:290200	7/28 (25%)
		C2H2 Zn finger	81..101	CDD:275368	10/20 (50%)
		C2H2 Zn finger	109..129	CDD:275368	4/20 (20%)
		C2H2 Zn finger	137..157	CDD:275368	5/19 (26%)
		zf-H2C2_2	149..174	CDD:290200	8/25 (32%)
		COG5048	<161..320	CDD:227381	39/116 (34%)
		C2H2 Zn finger	165..185	CDD:275368	0/19 (0%)
		CpXC	192..>241	CDD:291051	19/50 (38%)
		C2H2 Zn finger	193..213	CDD:275368	9/19 (47%)
		C2H2 Zn finger	221..241	CDD:275368	7/19 (37%)
		zf-H2C2_2	234..258	CDD:290200	12/23 (52%)
		C2H2 Zn finger	249..269	CDD:275368	6/20 (30%)
		C2H2 Zn finger	277..297	CDD:275368
		C2H2 Zn finger	304..324	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910