DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment eIF3f2 and MPND

DIOPT Version :9

Sequence 1:NP_610210.2 Gene:eIF3f2 / 35547 FlyBaseID:FBgn0033069 Length:286 Species:Drosophila melanogaster
Sequence 2:NP_001287791.1 Gene:MPND / 84954 HGNCID:25934 Length:501 Species:Homo sapiens


Alignment Length:233 Identity:45/233 - (19%)
Similarity:75/233 - (32%) Gaps:68/233 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    41 LGRNKEGHIEITNCFTVPHKEHSENKRIDLDMAYASEVLELNMF--------------------- 84
            |.||....:|:|:...:       ||....::|.:|.||.|..|                     
Human   248 LARNPHTLVEVTSFAAI-------NKFQPFNVAVSSNVLFLLDFHSHLTRSEVVGYLGGRWDVNS 305

  Fly    85 -------AYPNERVLGWFCTGKSVS---------RSASLIHDYYVRECCEGQPLHLLVDAALKNQ 133
                   |:|....||...|..::.         |..||:..|:........|....:||.:..|
Human   306 QMLTVLRAFPCRSRLGDAETAAAIEEEIYQSLFLRGLSLVGWYHSHPHSPALPSLQDIDAQMDYQ 370

  Fly   134 RLSTRLYCAVEMGVPGGTKGLMFSLV----PLEISNENSD-LVALRCIEKQSQQQASKQMERFVP 193
                       :.:.|.:.|....|.    |....|...: .::...:....:|:.|........
Human   371 -----------LRLQGSSNGFQPCLALLCSPYYSGNPGPESKISPFWVMPPPEQRPSDYGIPMDV 424

  Fly   194 ELAQVVDA--TRDMQHRLDLVLRYINDVLARKKKPDNV 229
            |:|.|.|:  |.|:.|.:.|::.:.      |..||.|
Human   425 EMAYVQDSFLTNDILHEMMLLVEFY------KGSPDLV 456

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
eIF3f2NP_610210.2 MPN_eIF3f 12..280 CDD:163695 45/233 (19%)
MPNDNP_001287791.1 MPN_2A_DUB 266..450 CDD:163698 35/200 (18%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG1310
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.