Protein Alignment eIF3f2 and BRCC3

DIOPT Version :9

• Sequence 1: NP_610210.2
• Gene: eIF3f2 / 35547
• FlyBaseID: FBgn0033069
• Length: 286
• Species: Drosophila melanogaster
• Sequence 2: XP_005274808.1
• Gene: BRCC3 / 79184
• HGNCID: 24185
• Length: 317
• Species: Homo sapiens
• Alignment Length: 245
• Identity: 41/245 - (16%)
• Similarity: 80/245 - (32%)
• Gaps: 98/245 - (40%)

  Fly    90 RVLGWFCTGKSVSRSASLIHDYYVRECCEGQPLHLLVDAALKNQRLSTRLYCAVEMGVPGGTKGL 154
            ||:||:.:...::...|.:.   ||.    |.::.::|.                     |..||
Human   117 RVVGWYHSHPHITVWPSHVD---VRT----QAMYQMMDQ---------------------GFVGL 153

  Fly   155 MFSLVPLEISNENSDLVALRCIEKQSQQQASKQMERFVPELAQVVDATRDM----QH-------- 207
            :||.. :|..|..:..|...|.:....|::|:.:.           ..||.    ||
Human   154 IFSCF-IEDKNTKTGRVLYTCFQSIQAQKSSESLH-----------GPRDFWSSSQHISIEGQKE 206

  Fly   208 -----RLDLVLRYINDVLARKKKPDNVVGRSLYAALTAVPLL----DSDKFR------------- 250
                 |:::.:..:         |...:|:....:...:|.:    :.|.:|
Human   207 EERYERIEIPIHIV---------PHVTIGKVCLESAVELPKILCQEEQDAYRRIHSLTHLDSVTK 262

  Fly   251 ----VMFNTNLRDMLMAIT--LSTMIKTQLEIS---------EKLSCMQD 285
                .:|..||...:.|::  |...::.:||.:         ||...||:
Human   263 IHNGSVFTKNLCSQMSAVSGPLLQWLEDRLEQNQQHLQELQQEKEELMQE 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF3f2	NP_610210.2	MPN_eIF3f	12..280	CDD:163695	38/238 (16%)
BRCC3	XP_005274808.1	MPN_BRCC36	13..293	CDD:163699	35/224 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1310
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900