DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eIF3f2 and Mpnd

DIOPT Version :9

Sequence 1:	NP_610210.2	Gene:	eIF3f2 / 35547	FlyBaseID:	FBgn0033069	Length:	286	Species:	Drosophila melanogaster
Sequence 2:	XP_038940132.1	Gene:	Mpnd / 681944	RGDID:	1589335	Length:	488	Species:	Rattus norvegicus

Alignment Length:	232	Identity:	45/232 - (19%)
Similarity:	72/232 - (31%)	Gaps:	69/232 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 RNKEGHIEITNCFTVPHKEHSENKRIDLDMAYASEVLELNMF----------------------- 84
            ||....:|:|:...:       ||....::|.:|.||.|..|
  Rat   236 RNPHTLVEVTSFAAI-------NKFQPFNVAVSSNVLFLLDFHCHLTRSEVVGYLGGRWDINNQM 293

  Fly    85 -----AYPNERVLGWFCTGKSVS---------RSASLIHDYYVRECCEGQPLHLLVDAALKNQRL 135
                 |:|....||...|..:|.         |..||:..|:........|....:||.::.|
  Rat   294 LTVLRAFPCRSRLGDPDTAATVEEEIHQVLFLRGLSLVGWYHSHPHSPAAPSLQDIDAQMEYQ-- 356

  Fly   136 STRLYCAVEMGVPGGTKGLMFSLV----PLEISN--ENSDLVALRCIEKQSQQQASKQMERFVPE 194
                     :.:.|...|....|.    |....|  ..|.:.....:....||:.|........|
  Rat   357 ---------LRLQGSNNGFQPCLALLCSPYYSGNPGPESKICPFWVMPPPEQQRPSDYGIPMDVE 412

  Fly   195 LAQVVDA--TRDMQHRLDLVLRYINDVLARKKKPDNV 229
            :|.|.|:  |.|:...:.:::.:.      |..||.|
  Rat   413 MAYVQDSFLTNDVLQEMMMLVEFY------KGAPDLV 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eIF3f2	NP_610210.2	MPN_eIF3f	12..280	CDD:163695	45/232 (19%)
Mpnd	XP_038940132.1	RAMA	57..157	CDD:408526
Mpnd	XP_038940132.1	MPN_2A_DUB	252..437	CDD:163698	36/201 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1310
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900