DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eIF3f2 and Mysm1

DIOPT Version :9

Sequence 1:	NP_610210.2	Gene:	eIF3f2 / 35547	FlyBaseID:	FBgn0033069	Length:	286	Species:	Drosophila melanogaster
Sequence 2:	XP_008762133.1	Gene:	Mysm1 / 298247	RGDID:	1311787	Length:	811	Species:	Rattus norvegicus

Alignment Length:	212	Identity:	46/212 - (21%)
Similarity:	78/212 - (36%)	Gaps:	55/212 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 QVMGTLLGRNKEGHIEITNCFTVPHKEHSENKRIDLD---MAYASEVLELNMFAYPNERVLGWFC 96
            :|:|.|.||..|....:..|...|....|...:.::|   ...|||.|.|...:     |:||:.
  Rat   580 EVIGLLGGRYSEADKVLEVCAAEPCNSLSTGLQCEMDPVSQTQASETLALRGCS-----VIGWYH 639

  Fly    97 TGKSVSRSASL--------IHDYYVRECCEGQPLHLLVDAALKNQRLS-TRLYCAV--EMGVPGG 150
            :..:...:.||        ...|:.|.  ..:.:.::|....::..|. :::.|.|  |...|.|
  Rat   640 SHPAFDPNPSLRDIDTQAKYQSYFSRG--GAKFIGMIVSPYNRSNPLPYSQITCLVISEELSPDG 702

  Fly   151 TKGLMF-------------------------------SLVPLE-ISNENSDLVALRCIEKQSQQQ 183
            |..|.:                               |.||:: |...:|||..|:.:.:..::.
  Rat   703 TYRLPYKFEVQQMLEEPQWELVFEKTRWIIEKYRLSHSSVPMDRIFRRDSDLTCLQKLLECLRKT 767

  Fly   184 ASKQMERFVPE--LAQV 198
            .||....|:.|  |.||
  Rat   768 LSKVANCFIAEEFLTQV 784

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eIF3f2	NP_610210.2	MPN_eIF3f	12..280	CDD:163695	46/212 (22%)
Mysm1	XP_008762133.1	Myb_DNA-binding	116..160	CDD:395191
		SWIRM	365..444	CDD:398234
		MPN_2A_DUB	554..736	CDD:163698	31/162 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1310
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900