DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eIF3f2 and Stambp

DIOPT Version :9

Sequence 1:	NP_610210.2	Gene:	eIF3f2 / 35547	FlyBaseID:	FBgn0033069	Length:	286	Species:	Drosophila melanogaster
Sequence 2:	NP_612540.1	Gene:	Stambp / 171565	RGDID:	619963	Length:	424	Species:	Rattus norvegicus

Alignment Length:	151	Identity:	32/151 - (21%)
Similarity:	61/151 - (40%)	Gaps:	33/151 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 DAALKNQ---RLSTRLYCAVEMG--VP------GGTKGLMFSLVPLEISNENSDLVALR-----C 175
            |.:|..|   |:.::|..|||:.  :|      .|.:.:..:.:..|..|.....:...     .
  Rat     6 DVSLPPQDRVRILSQLGSAVELNEDIPPRRYFRSGVEIIRMASIYSEEGNIEHAFILYNKYITLF 70

  Fly   176 IEKQSQQQASKQMERFVPELAQVVDATRDM------QHRLDLVLRYIND---VLARKKKPDNVVG 231
            |||..:.:..|  ...:||....|...:::      :.:.:|:.||..:   ...||||.:..:.
  Rat    71 IEKLPKHRDYK--SAIIPEKKDAVKKLKNVAFPKAEELKTELLKRYTKEYEQYKERKKKEEEELA 133

  Fly   232 RSLYAALTAVPL-LDSDKFRV 251
            |::     |:.. |:.:|.||
  Rat   134 RNI-----AIQQELEKEKQRV 149

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eIF3f2	NP_610210.2	MPN_eIF3f	12..280	CDD:163695	32/151 (21%)
Stambp	NP_612540.1	Interaction with CHMP3. /evidence=ECO:0000250	1..127		24/122 (20%)
		USP8_dimer	8..115	CDD:401063	20/108 (19%)
		Interaction with STAM1. /evidence=ECO:0000250	227..231
		MPN_AMSH_like	254..424	CDD:163697
		JAMM motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01182	335..348
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1310
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900