DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ptr and LOC110439381

DIOPT Version :9

Sequence 1:	NP_001246145.1	Gene:	Ptr / 35546	FlyBaseID:	FBgn0262867	Length:	1169	Species:	Drosophila melanogaster
Sequence 2:	XP_021331006.1	Gene:	LOC110439381 / 110439381	-ID:	-	Length:	261	Species:	Danio rerio

Alignment Length:	277	Identity:	76/277 - (27%)
Similarity:	130/277 - (46%)	Gaps:	34/277 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTCGISCVDKTLNKSFYHLGICIAKHPGYFIIIPVLLTLLCMTGYQQLKYQ--IDPEYLFSPIAG 63
            |.|...|:::.|:..|..||..|.:||..||::.:.:......|:..||.:  .|.|..|:|:.|
Zfish     1 MKCKTDCIERPLSLVFEKLGRLIGRHPVVFILLSLYVAAGLGAGFIFLKEREANDIEDQFTPVNG 65

  Fly    64 EGKTERAIVEQYFKVNYTHRFNVGRITRPGRFGRVIVITKDGDENMIRREVFQELRQLDNIIQNA 128
            ..|.:|.||.::|..  :..|:..|:...|.:..:|:....| ||::....|:|:..||.  |..
Zfish    66 PAKRDREIVAEHFPP--SDEFSQLRLMSEGTYASLIITDLQG-ENILTAAAFEEILALDR--QVK 125

  Fly   129 TTTYDGDTYTYKDNCARWENECFEN---DILNLDALMDDIEAGQLNLTFPFMFNPVTWDAHLFPV 190
            |..:.|:  |::..||:....|..|   ||:..:|.  ||::  :.:|:|..      |......
Zfish   126 TLQHLGN--TFEKLCAKIRGNCVSNAVLDIIRYNAA--DIDS--VTITYPIN------DKTFLGT 178

  Fly   191 FFGGTKLTEDNYVI-SVPAIQLVYFVTADTKRQDAKG-AEWEETFLRVVGNAENSGQFKHISVSY 253
            ..||.:...::.:: |..||:|.||:  |.|:  :|| |:|.|.|:....|..:..:     ||.
Zfish   179 TIGGVETQPNSSMLKSAKAIRLYYFL--DEKK--SKGNADWLEGFIEFFSNYTDQEK-----VSE 234

  Fly   254 FASRTLDHELEKNTKTV 270
            .....|.|.| .:|:|:
Zfish   235 DDREVLQHGL-THTQTI 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptr	NP_001246145.1	Patched	53..845	CDD:280598	61/223 (27%)
Ptr	NP_001246145.1	Sterol-sensing	295..442	CDD:289145
LOC110439381	XP_021331006.1	Patched	54..>233	CDD:330476	54/204 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D210960at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010