DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11211 and CLEC4M

DIOPT Version :9

Sequence 1:	NP_610208.1	Gene:	CG11211 / 35545	FlyBaseID:	FBgn0033067	Length:	176	Species:	Drosophila melanogaster
Sequence 2:	NP_055072.3	Gene:	CLEC4M / 10332	HGNCID:	13523	Length:	399	Species:	Homo sapiens

Alignment Length:	139	Identity:	33/139 - (23%)
Similarity:	59/139 - (42%)	Gaps:	22/139 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 DLTFYQKCNPLLQCNAYFSVAGFAEVNWLEANHVCNRVGAVLATVRNEEQHQLMLHYVNRKERIF 89
            |.||:|.       |.||  ...::.||.::...|..|.|.|..::..|:...:....:|
Human   271 DWTFFQG-------NCYF--MSNSQRNWHDSVTACQEVRAQLVVIKTAEEQNFLQLQTSR----- 321

  Fly    90 GNRTFWLGATNLVDRSYFWTWMSTGIPVT---YAQWSRREPKSDRTGQDACLVLGTDNLWHSEPC 151
            .||..|:|.::| ::...|.|:. |.|::   ...|:..||  :.:|.:.|....... |:...|
Human   322 SNRFSWMGLSDL-NQEGTWQWVD-GSPLSPSFQRYWNSGEP--NNSGNEDCAEFSGSG-WNDNRC 381

  Fly   152 QRKHNFICE 160
            ...:.:||:
Human   382 DVDNYWICK 390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11211	NP_610208.1	CLECT	49..160	CDD:153057	25/113 (22%)
CLEC4M	NP_055072.3	Endocytosis signal. /evidence=ECO:0000250	14..15
		transmembrane domain	44..71
		7 X approximate tandem repeats	108..269
		DUF342	<140..251	CDD:302792
		CLECT_DC-SIGN_like	268..391	CDD:153060	33/139 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1509611at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920