DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8343 and SFTPD

DIOPT Version :9

Sequence 1:	NP_610207.1	Gene:	CG8343 / 35544	FlyBaseID:	FBgn0040502	Length:	182	Species:	Drosophila melanogaster
Sequence 2:	NP_003010.4	Gene:	SFTPD / 6441	HGNCID:	10803	Length:	375	Species:	Homo sapiens

Alignment Length:	142	Identity:	37/142 - (26%)
Similarity:	58/142 - (40%)	Gaps:	21/142 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 AFSPF----------SLRDGRFAIGAFAKVNWFQAQATCAAYGYTLVSITSEQDQRSLRNFLFNY 95
            |||.:          |:.:..|....|.| .:.:||..|...|..|.|..|..:..:|:..:  .
Human   244 AFSQYKKVELFPNGQSVGEKIFKTAGFVK-PFTEAQLLCTQAGGQLASPRSAAENAALQQLV--V 305

  Fly    96 ARNQQDLLTDPLWTSGTDLASDNNWVWFSKGRAVNYRNFQNGLPGYSSDNRHCLGINGINGLWVN 160
            |:|:...|      |.||..::..:. :..|.::.|.|:..|.|.....:..|:.| ..||.|.:
Human   306 AKNEAAFL------SMTDSKTEGKFT-YPTGESLVYSNWAPGEPNDDGGSEDCVEI-FTNGKWND 362

  Fly   161 ENCSELRYFVCE 172
            ..|.|.|..|||
Human   363 RACGEKRLVVCE 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8343	NP_610207.1	CLECT	59..173	CDD:153057	31/114 (27%)
SFTPD	NP_003010.4	Collagen	46..98	CDD:189968
		Collagen	130..201	CDD:189968
		Surfac_D-trimer	224..269	CDD:286141	5/24 (21%)
		CLECT_collectin_like	262..375	CDD:153061	33/124 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910