DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8343 and clec-43

DIOPT Version :9

Sequence 1:	NP_610207.1	Gene:	CG8343 / 35544	FlyBaseID:	FBgn0040502	Length:	182	Species:	Drosophila melanogaster
Sequence 2:	NP_493859.2	Gene:	clec-43 / 187664	WormBaseID:	WBGene00019917	Length:	572	Species:	Caenorhabditis elegans

Alignment Length:	181	Identity:	48/181 - (26%)
Similarity:	82/181 - (45%)	Gaps:	33/181 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LFLVCLVFCSAWSLPESDLLPTSPAPGNDTAEEPQLPAFSPFSLRDGRFAIGAF-------AKVN 61
            :|::||:...| :...|.:  ||.||.|     .|.|::|  ...||...:..:       .|..
Worm     3 IFIICLLHIYA-TFSVSQI--TSRAPYN-----TQTPSYS--GCPDGFIVLNGYTCIQVSTTKKL 57

  Fly    62 WFQAQATCAAY-GYTLVSITSEQDQRSLRNFLFNYARNQQDLLTDPLWTS--GTDLASDNNWVWF 123
            :..|.:.|.:: |..||||.:..|.::|   .|:...      :||.|..  .|:.:|..||..:
Worm    58 FMDALSDCQSFPGGNLVSIHNSIDNKAL---AFSVTS------SDPKWIGLICTETSSPCNWTDY 113

  Fly   124 SKGRAVNYRNFQNGLPGYSSDNRHCLGINGIN-GLWVN-ENCSELRYFVCE 172
            |...: :|.||..|.|.....|...:.::|.: |.||: :..::|:| :||
Worm   114 SSDTS-SYSNFVAGNPNLDVGNYVYMLVSGSSAGRWVSADQYTQLKY-ICE 162

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8343	NP_610207.1	CLECT	59..173	CDD:153057	33/119 (28%)
clec-43	NP_493859.2	CLECT	36..162	CDD:214480	33/136 (24%)
		CLECT	188..320	CDD:214480
		CLECT	329..446	CDD:214480
		CUB	462..552	CDD:294042
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	51	1.000	Domainoid score	I7748
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000