Protein Alignment Cyp6w1 and CYP4F2

DIOPT Version :10

• Sequence 1: NP_610206.1
• Gene: Cyp6w1 / 35543
• FlyBaseID: FBgn0033065
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: NP_001073.3
• Gene: CYP4F2 / 8529
• HGNCID: 2645
• Length: 520
• Species: Homo sapiens
• Alignment Length: 572
• Identity: 140/572 - (24%)
• Similarity: 232/572 - (40%)
• Gaps: 138/572 - (24%)

  Fly     2 LLLLLLGSLTIVFYI--WQRRTLSFWERHGVKYIRPFP-------------VVGCTRE---FLTA 48
            |||||:|:..::.::  |   |.:|::  ..:.:|.||             :|..|.|   .||.
Human    20 LLLLLVGASWLLAHVLAW---TYAFYD--NCRRLRCFPQPPRRNWFWGHQGMVNPTEEGMRVLTQ 79

  Fly    49 KVPFFEQIQKFHEAPGFENEPFVGVYM-THRPALVIRDLELIKTV------MIKKFQYFNNRVLQ 106
            .|..:.|        ||:      |:| ...|.|.:...::|::|      :..|.::|.:.:
Human    80 LVATYPQ--------GFK------VWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFL-- 128

  Fly   107 TDPHNDALGYKNLFFARSPGWRELRTKISPVFTSGKIK--------------QMYPLMVKIGKNL 157
             :|.   || ..|..:....|...|..::|.|....:|              ..:.|:...|...
Human   129 -EPW---LG-DGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSAC 188

  Fly   158 QDSAERLGSGTEVQVKDLCSRFTTDLIATIAFGVEANALQDAKSEFFYHNRAIFSLTLSR----- 217
            .|..|.:            |..|.|.:....|..:::. |:..||:......:.:|...|
Human   189 LDMFEHI------------SLMTLDSLQKCVFSFDSHC-QEKPSEYIAAILELSALVSKRHHEIL 240

  Fly   218 -GIDFAIIFMIPALASLARVKLFSRETTKFIRSSVNYVLKERERT--------------GEKRND 267
             .||| :.::.|.....       |...:.:....:.|::||.||              ..|..|
Human   241 LHIDF-LYYLTPDGQRF-------RRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLD 297

  Fly   268 LIDILLALKREAAANPGKMSKEVDLDYLVAQAAVFQTAGFETSASTMTMTLYELAKNEALQDRLR 332
            .||:||..|.|    .||...:.|:.   |:|..|...|.:|:||.::..||.|||:...|:|.|
Human   298 FIDVLLLSKDE----DGKKLSDEDIR---AEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCR 355

  Fly   333 QEIVDFFGDED--HISYERIQEMPYLSQVVNETLRKYPIVGYIERECSQP---AEGERFTLEPFH 392
            ||:.:...|.:  .|.::.:..:|:|:..:.|:||.:|.|..|.|..:|.   .:|.
Human   356 QEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGR-------- 412

  Fly   393 NMELPHGMSIYMSTVAVHRDPQYWPDPEKYDPERFNSSNRDNLNMDAYMPFGVGPRNCIGMRLGL 457
              .:|.|:...:|....|.:|..|||||.|||.||:..|....:..|::||..|||||||....:
Human   413 --VIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAM 475

  Fly   458 LQSKLGLVHILRNHRF---HTCDKTIKKIEWAPTSPVMASKRDIILRVEKVS 506
            .:.|:.|...|...|.   ||..:...::       |:.::..:.||||.:|
Human   476 AEMKVVLALTLLRFRVLPDHTEPRRKPEL-------VLRAEGGLWLRVEPLS 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6w1	NP_610206.1	CYP6-like	67..498	CDD:410679	114/479 (24%)
CYP4F2	NP_001073.3	CYP4F	74..515	CDD:410772	120/506 (24%)