DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6w1 and CYP709B3

DIOPT Version :9

Sequence 1:	NP_001286145.1	Gene:	Cyp6w1 / 35543	FlyBaseID:	FBgn0033065	Length:	514	Species:	Drosophila melanogaster
Sequence 2:	NP_194501.1	Gene:	CYP709B3 / 828885	AraportID:	AT4G27710	Length:	518	Species:	Arabidopsis thaliana

Alignment Length:	515	Identity:	124/515 - (24%)
Similarity:	229/515 - (44%)	Gaps:	77/515 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLLLLLLGSLTIVFYIWQRRTLSFWERHGVKYIRPF---------PVVGCTREFLTAKVPFFEQI 56
            |.|:..:..||||..::.  ....|:...:..:||.         .:.|...:.|...:...:::
plant     1 MELISTINLLTIVLLLFV--VSKIWKACWILLLRPLMLSKRFKKQGISGPKYKILYGNLSEIKKM 63

  Fly    57 QKFHEA------PGFENEPFVGVYMTH-----------------RPALVIRDLELIKTVMIKKFQ 98
            :|  ||      |. .|:.|..|:..:                 :|.:.|.:.||.|.|:..||.
plant    64 KK--EADLCVLDPN-SNDIFPRVFPQYHQWMSQYGDTFLFWTGTKPTIYISNHELAKQVLSSKFG 125

  Fly    99 YFNNRVLQTDPHNDALGYKNLFFARSPGWRELRTKISPVFTSGKIKQMYPLMVKIGKNLQDSAER 163
            :....|.:  |....|..|.|.|.:...|...|..::|.|:..::|.|...|......:.:...:
plant   126 FTIIPVKR--PEVFILFGKGLSFIQGDDWIRHRRILNPAFSMDRLKAMTQPMGDCTLRIFEEWRK 188

  Fly   164 LGSGTEVQVK-DLCSRF---TTDLIATIAFGVE-ANALQDAKSEFFYHNRAIFSLTLSRGIDFAI 223
            .....||.:| ::...|   |.|:|||.|||.. |..::..:|:.......|.|||        .
plant   189 QRRNGEVLIKIEISKEFHKLTADIIATTAFGSSYAEGIELCRSQTELEKYYISSLT--------N 245

  Fly   224 IFMIPA---LASLARVKLFSRETTKFIRSSVNYV----LKERERTGEKRNDLIDILLALKREAAA 281
            :| ||.   |.:...:||:  |..|.:::|:..:    ||.:.:|....:||:.::|     .||
plant   246 VF-IPGTQYLPTPTNLKLW--ELHKKVKNSIKRIIDSRLKSKCKTYGYGDDLLGVML-----TAA 302

  Fly   282 NPGKMSKEVDLDYLVAQAAVFQTAGFETSASTMTMTLYELAKNEALQDRLRQEIVDFFGDEDHIS 346
            ...:..:::.:|.::.:...|..||..|::..:|.|...|:.::..|::||:|:.:..|.:....
plant   303 KSNEYERKMRMDEIIEECKNFYYAGQGTTSILLTWTTMLLSLHQGWQEKLREEVFNECGKDKIPD 367

  Fly   347 YERIQEMPYLSQVVNETLRKYPIVGYIERECSQPAEGERFTLEPFHNMELPHGMSIYMSTVAVHR 411
            .:...::..::.|:.|:||.|..|..|.||.:|..:        ..::|:|.|.||.:..:.:||
plant   368 TDTFSKLKLMNMVLMESLRLYGPVIKISREATQDMK--------VGHLEIPKGTSIIIPLLKMHR 424

  Fly   412 DPQYW-PDPEKYDPERF-NSSNRDNLNMDAYMPFGVGPRNCIGMRLGLLQSKLGLVHILR 469
            |...| .|.|:::|.|| |..::..::.:|.:||.:|||.||.....::::|..|..||:
plant   425 DKAIWGEDAEQFNPLRFENGISQATIHPNALLPFSIGPRACIAKNFAMVEAKTVLTMILQ 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6w1	NP_001286145.1	p450	34..501	CDD:278495	117/482 (24%)
CYP709B3	NP_194501.1	p450	9..517	CDD:299894	122/507 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810