DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6w1 and CYP72A14

DIOPT Version :9

Sequence 1:	NP_001286145.1	Gene:	Cyp6w1 / 35543	FlyBaseID:	FBgn0033065	Length:	514	Species:	Drosophila melanogaster
Sequence 2:	NP_188086.1	Gene:	CYP72A14 / 820696	AraportID:	AT3G14680	Length:	512	Species:	Arabidopsis thaliana

Alignment Length:	510	Identity:	126/510 - (24%)
Similarity:	212/510 - (41%)	Gaps:	81/510 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LGSLTIVFYIWQRRTLSF-W----------ERHGVKYIRPFPVVGCTREFL------TAK----- 49
            |..:.:.:::|  |||.: |          .|.|:......|::|..::.:      |:|
plant    12 LAVVVVSWWVW--RTLKWVWFTPKMLERSLRRQGLSGTSYTPLIGDFKKMISMFIEATSKPIKPT 74

  Fly    50 -------VPFFEQIQKFHEAPGFENEPFVGVYMTHRPALVIRDLELIKTVMIKKFQYFNNRVLQT 107
                   :|...|:.|.|   |..|..:.|..    |.:.|.|.|.||.|..|.:.:   :...|
plant    75 DDITPRVMPHPLQMLKTH---GRTNLTWFGPI----PTITIMDPEQIKEVFNKVYDF---QKAHT 129

  Fly   108 DPHNDALGYKNLFFARSPGWRELRTKISPVFTSGKIKQMYPLMVKIGKNLQDSAERL----GSGT 168
            .|.:..|| ..|.......|.:.|..|:|.|...|||.|..:..:....|....::|    ||..
plant   130 FPLSKILG-TGLVSYDGDKWAQHRRIINPAFHLEKIKNMVHVFHESCSELVGEWDKLVSDKGSSC 193

  Fly   169 EVQVKDLCSRFTTDLIATIAFGV---EANALQDAKSEFFYHNRAIFSLTLSRGIDFAIIFMIPAL 230
            ||.|....:..|.|:|:..|||.   |.:.:.:.::|........|..           |.||..
plant   194 EVDVWPGLTSMTADVISRTAFGSSYREGHRIFELQAELAQLVMQAFQK-----------FFIPGY 247

  Fly   231 ASL-----ARVKLFSRETTKFIRSSVNYVLKERERTGEKRNDLIDILLALKREAAANPGKMSKEV 290
            ..|     .|:|..:||....:|..:|...:.||.......||:.|||..........|..:::
plant   248 IYLPTKGNRRMKTAAREIQDILRGIINKRERARESGEAPSEDLLGILLESNLGQTEGNGMSTED- 311

  Fly   291 DLDYLVAQAAVFQTAGFETSASTMTMTLYELAKNEALQDRLRQEIVDFFGDEDHISYERIQEMPY 355
                ::.:..:|..||.||::..:..|:..|::::..|.|.|:|:...|||:.. ..|.:.::..
plant   312 ----MMEECKLFYLAGQETTSVLLVWTMVLLSQHQDWQARAREEVKQVFGDKQP-DTEGLNQLKV 371

  Fly   356 LSQVVNETLRKYPIVGYIERECSQPAEGERFTLEPFHNMELPHGMSIYMSTVAVHRDPQYW-PDP 419
            ::.::.|.||.||.|..:.|...:..:        ..::.||.|:.|.:..:.||||.:.| .|.
plant   372 MTMILYEVLRLYPPVVQLTRAIHKEMK--------LGDLTLPGGVQISLPVLLVHRDTELWGNDA 428

  Fly   420 EKYDPERFNSS-NRDNLNMDAYMPFGVGPRNCIGMRLGLLQSKLGLVHILRNHRF 473
            .::.||||... ::...|..::.||..|||.|||....||::|:.:..||:...|
plant   429 GEFKPERFKDGLSKATKNQVSFFPFAWGPRICIGQNFTLLEAKMAMSLILQRFSF 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6w1	NP_001286145.1	p450	34..501	CDD:278495	118/472 (25%)
CYP72A14	NP_188086.1	p450	24..512	CDD:299894	123/496 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900