DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6w1 and CYP72A11

DIOPT Version :9

Sequence 1:	NP_001286145.1	Gene:	Cyp6w1 / 35543	FlyBaseID:	FBgn0033065	Length:	514	Species:	Drosophila melanogaster
Sequence 2:	NP_188083.1	Gene:	CYP72A11 / 820693	AraportID:	AT3G14650	Length:	512	Species:	Arabidopsis thaliana

Alignment Length:	517	Identity:	122/517 - (23%)
Similarity:	207/517 - (40%)	Gaps:	101/517 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LTIVFYIWQRRTL-----------SFWERHGVKYIRPFPVVG------------------CTREF 45
            :.:.:::|  |||           |:..|.|:......|:||                  .|.:.
plant    15 VVVSWWVW--RTLQWVWFKPKMLESYLRRQGLAGTPYTPLVGDLKKNFSMRAEARSKPINLTDDI 77

  Fly    46 LTAKVPFFEQIQKFHEAPGFENEPFVGVYMTHRPALVIRDLELIKTVMIKKFQYFN------NRV 104
            ....||:..|:.|.|....|       .:....|.:.|.|.|.|..|:.|.:.:..      .|:
plant    78 TPRIVPYPLQMLKTHGRTFF-------TWFGAIPTITIMDPEQITEVLNKVYDFQKAHTFPLGRL 135

  Fly   105 LQTDPHNDALGYKNLFFARSPGWRELRTKISPVFTSGKIKQMYP--------LMVKIGKNLQDSA 161
            :.|    ..|.|.      ...|.:.|..|:|.|...|||.|.|        ::.|..|.:.|..
plant   136 IAT----GVLSYD------GDKWAKHRRIINPAFHLEKIKNMVPAFHQSCSEIVCKWDKLVSDKE 190

  Fly   162 ERLGSGTEVQVKDLCSRFTTDLIATIAFG---VEANALQDAKSEFFYHNRAIFSLTLSRGIDFAI 223
                |..||.|.......|.|:|:..|||   ||...:.:.::|.    ..:...|:.:.
plant   191 ----SSCEVDVWPGLVSMTADVISRTAFGSSCVEGQRIFELQAEL----AQLIIQTVRKA----- 242

  Fly   224 IFMIPALASL-----ARVKLFSRETTKFIRSSVNYVLKERERTGEKRNDLIDILLALKREAAANP 283
              .||..:.|     .|:|..:||....:|..||..|:.||......:||:.|||..........
plant   243 --FIPGYSYLPTKGNRRMKAKAREIQVILRGIVNKRLRAREAGEAPNDDLLGILLESNLGQTKGN 305

  Fly   284 GKMSKEVDLDYLVAQAAVFQTAGFETSASTMTMTLYELAKNEALQDRLRQEIVDFFGDEDHISYE 348
            |..:::     |:.:..:|...|.||::..:..|:..|::::..|.|.|:|:...|||::. ..|
plant   306 GMSTED-----LMEECKLFYFVGQETTSVLLVWTMVLLSQHQDWQARAREEVKQVFGDKEP-DAE 364

  Fly   349 RIQEMPYLSQVVNETLRKYPIVGYIERECSQPAEGERFTLEPFHNMELPHGMSIYMSTVAVHRDP 413
            .:.::..::.::.|.||.||.:..:.|...:..|        ..::.||.|:.|.:..:.|.||.
plant   365 GLNQLKVMTMILYEVLRLYPPIPQLSRAIHKEME--------LGDLTLPGGVLINLPILLVQRDT 421

  Fly   414 QYW-PDPEKYDPERFNSS-NRDNLNMDAYMPFGVGPRNCIGMRLGLLQSKLGLVHILRNHRF 473
            :.| .|..::.|:||... ::...|..::.||..|.|.|||....||::|:.:..||:...|
plant   422 ELWGNDAGEFKPDRFKDGLSKATKNQASFFPFAWGSRICIGQNFALLEAKMAMALILQRFSF 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6w1	NP_001286145.1	p450	34..501	CDD:278495	115/482 (24%)
CYP72A11	NP_188083.1	p450	24..512	CDD:299894	120/506 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900